The PICU Data Collaborative: A Novel, Multi-Institutional, Pediatric Critical Care Dataset

Reid W D Farris¹, Sareen S Shah^{2

3}, Tellen D Bennett⁴, Stephanie R Brown⁵, Timothy T Cornell⁶, Adam C Dziorny⁷, Alysia Flynn³, Jocelyn Grunwell⁵, Julia A Heneghan⁸, Curt E Kennedy⁹, Aleksandra Kretsu³, Eneida Mendonca¹⁰, Akira Nishisaki¹¹, Colin Rogerson¹², Daniel S Tawfik⁶, Randall C Wetzel^{3

13}, L Nelson Sanchez-Pinto¹⁴; PICU Data Collaborative

Affiliations

¹ Department of Pediatrics (Critical Care Medicine), University of Washington School of Medicine, Seattle Children's Hospital, Seattle, WA.
² Department of Pediatrics (Critical Care Medicine), Cedars-Sinai Medical Center, Los Angeles, CA.
³ Laura P. and Leland K. Whittier Virtual Pediatric Intensive Care Unit, University of Southern California Keck School of Medicine, Children's Hospital Los Angeles, Los Angeles, CA.
⁴ Departments of Biomedical Informatics and Pediatrics (Critical Care Medicine), University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, CO.
⁵ Department of Pediatrics (Critical Care Medicine), Emory University School of Medicine, Atlanta, GA.
⁶ Department of Pediatrics (Critical Care Medicine), Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA.
⁷ Departments of Pediatrics (Critical Care Medicine) and Biomedical Engineering, University of Rochester School of Medicine, Rochester, NY.
⁸ Department of Pediatrics (Critical Care Medicine), University of Minnesota Medical School, Minneapolis, MN.
⁹ Department of Pediatrics (Critical Care Medicine), Baylor College of Medicine, Texas Children's Hospital, Houston, TX.
¹⁰ Department of Pediatrics (Biomedical Informatics), University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
¹¹ Department of Anesthesia (Critical Care Medicine), University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
¹² Department of Pediatrics (Critical Care Medicine), Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN.
¹³ Departments of Pediatrics and Anesthesiology (Critical Care Medicine), University of Southern California Keck School of Medicine, Children's Hospital Los Angeles, Los Angeles, CA.
¹⁴ Departments of Pediatrics (Critical Care Medicine) and Preventive Medicine (Health & Biomedical Informatics), Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.

PMID: 40304542
PMCID: PMC12221772 (available on 2026-04-30)
DOI: 10.1097/PCC.0000000000003758

The PICU Data Collaborative: A Novel, Multi-Institutional, Pediatric Critical Care Dataset

Reid W D Farris et al. Pediatr Crit Care Med. 2025.

. 2025 Jul 1;26(7):e941-e951.

doi: 10.1097/PCC.0000000000003758. Epub 2025 Apr 30.

Authors

Affiliations

¹ Department of Pediatrics (Critical Care Medicine), University of Washington School of Medicine, Seattle Children's Hospital, Seattle, WA.
² Department of Pediatrics (Critical Care Medicine), Cedars-Sinai Medical Center, Los Angeles, CA.
³ Laura P. and Leland K. Whittier Virtual Pediatric Intensive Care Unit, University of Southern California Keck School of Medicine, Children's Hospital Los Angeles, Los Angeles, CA.
⁴ Departments of Biomedical Informatics and Pediatrics (Critical Care Medicine), University of Colorado School of Medicine, Children's Hospital Colorado, Aurora, CO.
⁵ Department of Pediatrics (Critical Care Medicine), Emory University School of Medicine, Atlanta, GA.
⁶ Department of Pediatrics (Critical Care Medicine), Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, CA.
⁷ Departments of Pediatrics (Critical Care Medicine) and Biomedical Engineering, University of Rochester School of Medicine, Rochester, NY.
⁸ Department of Pediatrics (Critical Care Medicine), University of Minnesota Medical School, Minneapolis, MN.
⁹ Department of Pediatrics (Critical Care Medicine), Baylor College of Medicine, Texas Children's Hospital, Houston, TX.
¹⁰ Department of Pediatrics (Biomedical Informatics), University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
¹¹ Department of Anesthesia (Critical Care Medicine), University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
¹² Department of Pediatrics (Critical Care Medicine), Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN.
¹³ Departments of Pediatrics and Anesthesiology (Critical Care Medicine), University of Southern California Keck School of Medicine, Children's Hospital Los Angeles, Los Angeles, CA.
¹⁴ Departments of Pediatrics (Critical Care Medicine) and Preventive Medicine (Health & Biomedical Informatics), Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.

PMID: 40304542
PMCID: PMC12221772 (available on 2026-04-30)
DOI: 10.1097/PCC.0000000000003758

No abstract available

Keywords: critical care; database; machine learning; pediatrics.

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Conflict of interest statement

Dr. Bennett’s institution received funding from the National Institute of Child Health and Human Development, the National Heart, Lung, and Blood Institute, and the Centers for Disease Control and Prevention. Drs. Dziorny and Heneghan received support for article research from the National Institutes of Health (NIH). Drs. Shah and Flynn received support for article research from the Laura P. and Leland K. Whittier Foundation. Dr. Heneghan’s institution received funding from the National Center for Advancing Translational Sciences. Ms. Kretsu’s institution received funding from the L.K. Whittier Foundation; she received support for article research from the L.K. Whittier Foundation; and she disclosed work for hire. Dr. Nishisaki’s institution received funding from the Agency for Healthcare Research and Quality, the NIH, and Chiesi. Dr. Wetzel’s institution received funding from the Whittier Family Foundation. The remaining authors have disclosed that they do not have any potential conflicts of interest.

References

1. Killien EY, Keller MR, Watson RS, et al. : Epidemiology of Intensive Care Admissions for Children in the US From 2001 to 2019. JAMA Pediatr 2023; 177:506–515 - PMC - PubMed
1. Horak RV, Griffin JF, Brown A-M, et al. : Growth and Changing Characteristics of Pediatric Intensive Care 2001–2016. [Internet]. Critical Care Medicine 2019; 47:1135–1142 - PubMed
1. Heneghan JA, Rogerson C, Goodman DM, et al. : Epidemiology of Pediatric Critical Care Admissions in 43 United States Children’s Hospitals, 2014–2019*. Pediatr Crit Care Med 2022; 23:484–492 - PubMed
1. Cifra CL, Custer JW, Singh H, et al. : Diagnostic Errors in Pediatric Critical Care: A Systematic Review*. Pediatr Crit Care Med 2021; 22:701–712 - PMC - PubMed
1. Weiss SL, Fitzgerald JC, Pappachan J, et al. : Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study. [Internet]. Am J Respir Crit Care Med 2015; 191:1147–1157 - PMC - PubMed

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The PICU Data Collaborative: A Novel, Multi-Institutional, Pediatric Critical Care Dataset

Affiliations

The PICU Data Collaborative: A Novel, Multi-Institutional, Pediatric Critical Care Dataset

Authors

Affiliations

Conflict of interest statement

References

Grants and funding

LinkOut - more resources

Full Text Sources