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. 1985 Jun:15 Suppl C:1-4.
doi: 10.1093/jac/15.suppl_c.1.

Synthesis and preliminary in-vitro profile of Sch 34343--a new penem antibacterial agent

A K Ganguly, A Afonso, V M Girijavallabhan, S McCombie

Synthesis and preliminary in-vitro profile of Sch 34343--a new penem antibacterial agent

A K Ganguly et al. J Antimicrob Chemother. 1985 Jun.

Abstract

Sch 34343, a new penem antibiotic, has been synthesized by several routes and found to be highly active against both aerobic and anaerobic Gram-positive and Gram-negative organisms (except Pseudomonas). It has excellent beta-lactamase stability and is bactericidal. The synthetic routes to Sch 34343 and its in-vitro activity compared with other structurally related penems are discussed.

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