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. 2025 Apr 30;15(4):e090256.
doi: 10.1136/bmjopen-2024-090256.

Effects of pre-CABG program on discharge readiness and surgery outcomes for patients undergoing elective CABG surgery: a study protocol for a randomised control trial

Affiliations

Effects of pre-CABG program on discharge readiness and surgery outcomes for patients undergoing elective CABG surgery: a study protocol for a randomised control trial

Pouya Dolat Abadi et al. BMJ Open. .

Abstract

Introduction: Cardiovascular diseases, a leading cause of death globally, impose significant health and economic burdens, particularly in countries like Iran. Coronary artery bypass grafting (CABG) is a common intervention for ischaemic heart disease, yet it entails a long recovery process with potential complications and psychological impacts. This study aims to evaluate the effectiveness of a prehabilitation programme (pre-CABG) on postoperative outcomes and discharge readiness in patients undergoing elective CABG.

Methods and analysis: This randomised controlled trial involves 60 patients diagnosed with coronary artery disease at Imam Khomeini Hospital Complex, Tehran. Participants will be randomly assigned to either the intervention group, receiving the pre-CABG programme, or the control group, receiving standard care. The pre-CABG programme includes patient education, stress management techniques, respiratory muscle training and nutritional guidance. Primary outcomes include discharge readiness, duration of intubation, Intensive Care Uniy (ICU) stay, occurrence of atelectasis, onset of mobility, hospital stay and levels of anxiety and depression. Secondary outcomes include the rate of 30-day readmissions. Data collection will involve standardised scales and checklists administered at various stages preoperation and postoperation.

Ethics and dissemination: The research study has received approval from the Research Ethics Committee at Tehran University of Medical Sciences' School of Nursing and Midwifery and Rehabilitation. All participants must provide written consent for their involvement in this study. The findings will be shared with appropriate groups and published in peer-reviewed journals.

Trial registration number: The study is registered with the Iranian Registry of Clinical Trials under the ID IRCT20231019059768N1.

Keywords: Cardiovascular Disease; Coronary intervention; Nursing Care; Randomised Controlled Trial.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1. Flowchart showing patient allocation to intervention and control groups. HADS, Hospital Anxiety and Depression Scale; RHDS, Readiness for Hospital Discharge Scale.** COPD Chronic Obstructive Pulmonary Disease.** RHDS-RN Readiness for Hospital Discharge Scale based on Registered Nurses’ Score

References

    1. Amini M, Zayeri F, Salehi M. Trend analysis of cardiovascular disease mortality, incidence, and mortality-to-incidence ratio: results from global burden of disease study 2017. BMC Public Health. 2021;21:401. doi: 10.1186/s12889-021-10429-0. - DOI - PMC - PubMed
    1. Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet. 2012;380:2095–128. doi: 10.1016/S0140-6736(12)61728-0. - DOI - PMC - PubMed
    1. Sokhteh ASD, Mofrad ZP, Yaghoubinia F. The effectiveness of rehabilitation-education program on risk factors in patients with coronary artery disease. 2020
    1. Gaziano TA, Bitton A, Anand S, et al. Growing epidemic of coronary heart disease in low- and middle-income countries. Curr Probl Cardiol. 2010;35:72–115. doi: 10.1016/j.cpcardiol.2009.10.002. - DOI - PMC - PubMed
    1. Roth GA, Mensah GA, Johnson CO, et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study. J Am Coll Cardiol. 2020;76:2982–3021. doi: 10.1016/j.jacc.2020.11.010. - DOI - PMC - PubMed

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