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Editorial
. 2025 Mar 31;17(3):e81528.
doi: 10.7759/cureus.81528. eCollection 2025 Mar.

The Clinical Significance of the Magee Equations in Breast Cancer Prognostication

Shubhneet Bal  1 , Roopa Kumari  2
Affiliations
Editorial

The Clinical Significance of the Magee Equations in Breast Cancer Prognostication

Shubhneet Bal et al. Cureus. .

Abstract

The landscape of breast cancer management has been revolutionized by advancements in molecular diagnostics, yet accessibility and cost remain significant barriers for many patients. Limited-resource settings often face significant challenges in accessing expensive molecular tests, which can impact timely diagnosis and treatment decisions. The Magee equations present a practical, cost-effective solution that can bridge this gap, ensuring that patients, regardless of their financial or geographic limitations, receive appropriate and timely treatment. Originally developed at the University of Pittsburgh Medical Center, these equations offer a reliable alternative for estimating recurrence scores without the prohibitive costs associated with genomic assays.

Keywords: breast cancer; gene expression assay; magee equation; neoadjuvant therapy (nac); oncotype dx.

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Conflict of interest statement

Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

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