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. 2025 Apr 29:24741264251333200.
doi: 10.1177/24741264251333200. Online ahead of print.

Wavefront Aberrometry in Pseudophakic Patients Before and After Vitrectomy for Bothersome Floaters

Daniel A Adelberg  1   2 , Mark T Parsons  2
Affiliations

Wavefront Aberrometry in Pseudophakic Patients Before and After Vitrectomy for Bothersome Floaters

Daniel A Adelberg et al. J Vitreoretin Dis. .

Abstract

Introduction: To investigate whether the outcome of patients with persistent bothersome floaters who are managed with vitrectomy can be correlated with improvements in higher-order aberrations with wavefront aberrometry. Methods: Pseudophakic patients who had 27-gauge vitrectomy for persistent floaters and whose clinical assessment included preoperative and postoperative wavefront aberrometry were included. The primary outcome was the change in the higher-order aberration percentage measured by wavefront aberrometry. Results: The study included 76 eyes of 66 patients with a mean age (±SD) of 67.8 ± 7.5 years. The Snellen visual acuity improved from 20/32 preoperatively to 20/25 postoperatively (P = .004). Wavefront aberrometry showed a highly significant reduction in the higher-order aberration percentage (P < .000001), with a mean preoperative percentage of 53.9 and a mean postoperative percentage of 38.3. Subgroup analysis found a significant reduction in patients with no previous posterior capsulotomy (P = .001), previous neodymium:YAG capsulotomy (P < .000001), a monofocal intraocular lens (IOL) (P < .000001), and a multifocal IOL (P = .006). There was no significant difference in the mean preoperative and postoperative pupil size, sphere, cylinder, or spherical equivalent. Conclusions: Wavefront aberrometry demonstrates an objective, significant reduction in higher-order aberrations immediately after vitrectomy in pseudophakic patients with bothersome floaters.

Keywords: PPV; aberrations; myodesopsia; opacities; ophthalmology; optics; refractive; retina; vision; vitreous.

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Conflict of interest statement

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Mean preoperative (blue) and postoperative (red) wavefront data. (A) Higher-order aberrations percentage (HO%). (B) Root-mean-square HOAs (RMS HO), RMS, and total aberrations. *Statistically significant (P < .05).
Figure 2.
Figure 2.
Mean preoperative (blue) and postoperative (red) Zernike polynomials. *Statistically significant (P < .05).
See this image and copyright information in PMC

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