Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Feb;15(2):500-9.
doi: 10.1128/iai.15.2.500-509.1977.

Purification of a monocytosis-producing activity from Listeria monocytogenes

S B Galsworthy, S M Gurofsky, R G Murray

Purification of a monocytosis-producing activity from Listeria monocytogenes

S B Galsworthy et al. Infect Immun. 1977 Feb.

Abstract

The monocytosis-producing activity (MPA) from Listeria monocytogenes is shown to be associated with the cell envelope. Both MPA and immunosuppressive activity were readily extracted with aqueous solvents and separated as two independent activities by gel filtration and ion-exchange chromatography. As little as 10 microng of the resulting MPA-containing fraction caused a ninefold elevation in the level of circulating monocytes. The molecular weight of the fraction was approximately 22,000, and it contained phosphorus and carbohydrate.

PubMed Disclaimer

References

    1. Z Immunitatsforsch Exp Klin Immunol. 1975 Jul;149(2-4):289-94 - PubMed
    1. J Immunol. 1975 Mar;114(3):1132-4 - PubMed
    1. Infect Immun. 1975 May;11(5):949-54 - PubMed
    1. Cell Immunol. 1975 Jun;17(2):418-22 - PubMed
    1. Infect Immun. 1975 Sep;12(3):647-55 - PubMed