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. 2025 Apr 17:16:1547303.
doi: 10.3389/fimmu.2025.1547303. eCollection 2025.

IgA and the gut-vagina axis

Affiliations

IgA and the gut-vagina axis

Kazuhide Takada. Front Immunol. .
No abstract available

Keywords: IgA; Lactobacillus; gut-vagina axis; microbiota; probiotics.

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Conflict of interest statement

The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Hypothetical Schematic of colonization of the vagina by Lactobacillus. 1, 2: Lactobacillus-reactive and Integrin αEβ7+ memory/effector cells migrate from the small intestine to the vagina and produce Lactobacillus-specific IgA. 3: IgA-coated Lactobacillus may directly migrate from the gut to the vagina. 4: IgA-coated Lactobacillus promotes its stable colonization in the vagina.

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