Simplifying Sotatercept in Pulmonary Arterial Hypertension: Genetic Context Meets Treatment Response
- PMID: 40315138
- PMCID: PMC12175923
- DOI: 10.1164/rccm.202503-0539ED
Simplifying Sotatercept in Pulmonary Arterial Hypertension: Genetic Context Meets Treatment Response
Comment on
-
Consistent Safety and Efficacy of Sotatercept for Pulmonary Arterial Hypertension in BMPR2 Mutation Carriers and Noncarriers: A Planned Analysis of a Phase II, Double-Blind, Placebo-controlled Clinical Trial (PULSAR).Am J Respir Crit Care Med. 2025 Jun;211(6):1028-1037. doi: 10.1164/rccm.202409-1698OC. Am J Respir Crit Care Med. 2025. PMID: 40035659 Clinical Trial.
References
-
- Humbert M, Sitbon O, Chaouat A, Bertocchi M, Habib G, Gressin V. et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation . 2010;122:156–163. - PubMed
-
- Barst RJ, Rubin LJ, Long WA, McGoon MD, Rich S, Badesch DB. et al. Primary Pulmonary Hypertension Study Group. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med . 1996;334:296–301. - PubMed
Publication types
LinkOut - more resources
Full Text Sources