Dulling the Double-edged Sword: Expanding the Arsenal of Diaphragm Protection in Early Respiratory Failure

Heder de Vries^{1

2}, Timothy Girard^{3

4}

Affiliations

¹ Intensive Care Department Amsterdam University Medical Center Amsterdam, the Netherlands.
² Amsterdam Cardiovascular Sciences Research Institute Amsterdam, the Netherlands.
³ Center for Research, Investigation, and Systems Modeling of Acute Illness.
⁴ Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.

Editorial

Heder de Vries et al. Am J Respir Crit Care Med. 2025 Aug.

. 2025 Aug;211(8):1331-1333.

doi: 10.1164/rccm.202503-0542ED.

Heder de Vries^{1

2}, Timothy Girard^{3

4}

¹ Intensive Care Department Amsterdam University Medical Center Amsterdam, the Netherlands.
² Amsterdam Cardiovascular Sciences Research Institute Amsterdam, the Netherlands.
³ Center for Research, Investigation, and Systems Modeling of Acute Illness.
⁴ Department of Critical Care Medicine University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.

No abstract available

Figures

Continuous On-Demand Diaphragm Neurostimulation to Prevent Diaphragm Inactivity During Mechanical Ventilation: A Phase 1 Clinical Trial (STIMULUS).
Morris IS, Bassi T, Bellissimo CA, Bootjeamjai P, Roman-Sarita G, de Perrot M, Donahoe L, McRae K, Dianti J, Del Sorbo L, Keshavjee S, Cypel M, Reynolds SC, Dres M, Thakkar V, Mehta N, Brochard L, Ferguson ND, Goligher EC. Morris IS, et al. Am J Respir Crit Care Med. 2025 Aug;211(8):1442-1451. doi: 10.1164/rccm.202407-1483OC. Am J Respir Crit Care Med. 2025. PMID: 40043207 Clinical Trial.

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