Preparation and properties of derivatives of virginiamycin S
- PMID: 403168
- DOI: 10.7164/antibiotics.30.141
Preparation and properties of derivatives of virginiamycin S
Abstract
Reduction of virginiamycin S with sodium borohydride produces allo- and normal-dihydro-virginiamycin S. Reduction of the tosylhydrazone of virginiamycin S with sodium cyanoborohydride affords deoxyvirginiamycin S. These compounds are less active than virginiamycin S. Like virginiamycin S they enhance the activity of virginiamycin M1.
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