Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Apr 30:21:327-343.
doi: 10.2147/VHRM.S488465. eCollection 2025.

Potential of Fruits to Improve Dyslipidemias: A Pilot Review

Miguel Angel Flores Flores #  1 , Luis Antonio Flores Flores #  2 , Serafín Dernali Romero Yupanqui #  3
Affiliations
Review

Potential of Fruits to Improve Dyslipidemias: A Pilot Review

Miguel Angel Flores Flores et al. Vasc Health Risk Manag. .

Abstract

Dyslipidemia is a condition characterized by excessive lipids in the blood plasma, including triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and decreased levels of high-density lipoprotein cholesterol (HDL-C), which is generated mostly due to obesity. This study aims to summarize research conducted on rats and humans regarding the potential of eight fruits in reducing dyslipidemia and their associated health benefits (eg, reduction of free radicals, hypoglycemic effects, weight reduction, lowering of blood pressure, and anti-inflammatory properties). The studied fruits include pomegranate, star fruit, Rosa roxburghii, pineapple, tree tomato, coffee, apple, and passion fruit. Various parts of these fruits, such as the root, leaves, stem, peel, and pulp, were analyzed for their effects. These fruits are edible, widely available, and cost-effective when purchased during the harvest season (Graphical abstract).

Keywords: benefits; dyslipidemias; fruits; humans; rats.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

None
Graphical abstract
Figure 1
Figure 1
Fruits that prevent dyslipidemia. Created in BioRender. Flores Flores, M. (2025) https://BioRender.com/i31f701.
Figure 2
Figure 2
Bioactive compounds present in Pomegranate (Punica granatum L.) and their effect in vivo. Created in BioRender. Flores Flores, M. (2025) https://BioRender.com/e75a587.
Figure 3
Figure 3
Bioactive compounds present in Starfruit (Averrhoa carambola) and their effect in vivo.BioRender. Flores Flores, M. (2025) https://BioRender.com/e75a587.
Figure 4
Figure 4
Bioactive compounds present in Rosa roxburghii (Rosa roxburghii tratt) and their effect in vivo. Created in BioRender. Flores Flores, M. (2025) https://BioRender.com/l71g160.
Figure 5
Figure 5
Bioactive compounds present in Pineapple (Ananas comosus) and their effect in vivo. Created in BioRender. Flores Flores, M. (2025) https://BioRender.com/r70d826.
Figure 6
Figure 6
Bioactive compounds present in Tree tomato (Solanum betaceum) and their effect in vivo. Created in BioRender. Flores Flores, M. (2025) https://BioRender.com/t90c849.
Figure 7
Figure 7
Bioactive compounds present in Coffee (Coffea) and their effect in vivo. Created in BioRender. Flores Flores, M. (2025) https://BioRender.com/o96y523.
Figure 8
Figure 8
Bioactive compounds present in Apple (Malus domestica) and their effect in vivo. Created in BioRender. Flores Flores, M. (2025) https://BioRender.com/t54q725.
Figure 9
Figure 9
Bioactive compounds present in Passion fruit (Passiflora edulis) and their effect in vivo. Created in BioRender. Flores flores, M. (2025) https://BioRender.com/u41t501.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Chrigui S, Taieb SH, Jemai H, et al. Anti-obesity and anti-dyslipidemic effects of salicornia arabica decocted extract in tunisian psammomys obesus fed a high-calorie diet. Foods. 2023;12(6):1185. doi:10.3390/FOODS12061185 - DOI - PMC - PubMed
    1. Berberich AJ, Hegele RA. A modern approach to dyslipidemia. Endocr Rev. 2022;43(4):611–653. doi:10.1210/ENDREV/BNAB037 - DOI - PMC - PubMed
    1. Fahmy H, Hegazi N, El-Shamy S, Farag MA. Pomegranate juice as a functional food: a comprehensive review of its polyphenols, therapeutic merits, and recent patents. Food Funct. 2020;11(7):5768–5781. doi:10.1039/D0FO01251C - DOI - PubMed
    1. Isas AS, Escobar F, Álvarez-Villamil E, et al. Fermentation of pomegranate juice by lactic acid bacteria and its biological effect on mice fed a high-fat diet. Food Biosci. 2023;53:102516. doi:10.1016/j.fbio.2023.102516 - DOI
    1. Halim NAA, Karim CF, Mohammed IK, et al. Anti-obesity effect of methanolic extracts of local punica granatum in high-fat diet-induced obese rats. Malaysian J Med Health Sci. 2023;18(2):228–236. doi:10.47836/MJMHS.19.2.33 - DOI

LinkOut - more resources