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Case Reports
. 2025 Apr 3;17(4):e81649.
doi: 10.7759/cureus.81649. eCollection 2025 Apr.

Detection, Prevention, and Treatment of Asymptomatic Myxoma in a Young Adult Patient: A Case Report

Yuta Murai  1 , Kouki Nakashima  1
Affiliations
Case Reports

Detection, Prevention, and Treatment of Asymptomatic Myxoma in a Young Adult Patient: A Case Report

Yuta Murai et al. Cureus. .

Abstract

We present a case of myxoma originating from the right ventricular outflow tract. The patient was referred to our clinic after detecting a heart murmur at a routine school medical check-up, which is unique to Japan. He was treated with tumor resection and cryoablation to prevent recurrence. Cryoablation after tumor removal has the potential to prevent the recurrence of cardiac tumors. This case further emphasized the importance of regular school medical check-ups because it prevented sudden death.

Keywords: cardiac murmur; cardiac myxoma; cryoablation; school health check-up; ventricular outflow tract.

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Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Echocardiographic view of the tumor in right ventricular outflow tract
A. Parasternal long-axis tomogram and echocardiographic view of the tumor in the right ventricular outflow tract; B. Short-axis tomogram of aortic valve level and echocardiographic view of the tumor in the right ventricular outflow tract
Figure 2
Figure 2. CT images of the tumour in the right ventricular outflow tract
Axial (A) and sagittal (B) views of the tumor in the right ventricular outflow tract on CT. CT: computed tomography
Figure 3
Figure 3. Sagittal view of the MRI showing the tumor in the right ventricular outflow tract
The red arrow indicates the tumor in the right ventricular outflow tract, revealing high signal intensity within the tumor on T2-weighted imaging, reflecting the mucin contents of the tumor. MRI: magnetic resonance imaging; Main PA: main pulmonary artery; RV: right ventricle; LV: left ventricle
Figure 4
Figure 4. Surgical treatment of the myxoma
A. Intraoperative view, the red arrow indicates the tumor from the right atrium into the right ventricle; B. Intraoperative view of the entire tumor after pressing on the right ventricular outflow tract from the outside of the heart; C. Cryoablation was performed at the root of the tumor.
Figure 5
Figure 5. Macroscopic and histopathological findings of cardiac myxoma
A. Resected myxoma; the maximum diameter is 4 cm; B. Spindle-shaped tumor cells are interspersed within a myxoid stroma. There are no malignant findings. (hematoxylin and eosin staining; bar = 100 μm; magnification × 200); C. Bleeding and thrombus formation are seen in the tumor (hematoxylin and eosin staining; bar = 100 μm; magnification × 200).
Figure 6
Figure 6. Postoperative echocardiographic view of the tumour in the right ventricular outflow tract
A parasternal long axis tomogram (A) and a short-axis tomogram of the aortic valve level (B) show no residual tumor.
See this image and copyright information in PMC

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