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Review
. 2025 Jan;17(1):60-67.
doi: 10.34172/mejdd.2025.409. Epub 2025 Jan 31.

The Interplay of Coping Strategies and Quality of Life in Inflammatory Bowel Disease: A Systematic Review

Lining Wang  1 , Norafisyah Makhdzir  1 , Zarina Haron  1
Affiliations
Review

The Interplay of Coping Strategies and Quality of Life in Inflammatory Bowel Disease: A Systematic Review

Lining Wang et al. Middle East J Dig Dis. 2025 Jan.

Abstract

Background: This systematic review, grounded in coping theory, examines the relationship between coping strategies and quality of life (QoL) in patients with inflammatory bowel disease. It synthesizes current findings and guides future research to address existing knowledge gaps.

Methods: A comprehensive search of Scopus, PubMed, Google Scholar, and Web of Science (from April 2000 to April 2024) identified 17 peer-reviewed studies.

Results: Coping strategies directly and indirectly influence the QoL of patients with inflammatory bowel disease (IBD). Adaptive strategies, such as problem-solving and seeking social support, consistently improve QoL even in patients with active disease by promoting better disease management and emotional well-being. Maladaptive strategies, such as avoidance and emotional detachment, lead to decreased QoL and increased psychological distress. In addition, self-efficacy and psychological resilience play a key role in mediating the relationship between coping and QoL. However, coping strategies differ by disease stage and between demographic groups.

Conclusion: This study identifies significant gaps in research, such as limited multi-center and longitudinal studies, cross-cultural inconsistencies, and insufficient focus on specific populations. These gaps restrict understanding of the long-term effects of coping strategies. Future research should combine quantitative and qualitative methods to better capture patients' experiences, aiding the development of personalized interventions.

Keywords: Coping strategies; Coping theory framework; Inflammatory bowel disease; Quality of life.

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Conflict of interest statement

Competing Interests The authors have no conflicts of interest to declare related to this work.

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References

    1. Alatab S, Ghajarieh Sepanlou S, Ikuta K, Vahedi H, Bisignano C, Safiri S, et al. The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol Hepatol. 2020;5(1):17–30. doi: 10.1016/s2468-1253(19)30333-4. - DOI - PMC - PubMed
    1. Lungaro L, Costanzini A, Manza F, Barbalinardo M, Gentili D, Guarino M, et al. Impact of female gender in inflammatory bowel diseases: a narrative review. J Pers Med. 2023;13(2):165. doi: 10.3390/jpm13020165. - DOI - PMC - PubMed
    1. Momayez Sanat Z, Vahedi H, Malekzadeh R, Fanni Z. Epidemiologic profile of inflammatory bowel disease in Eastern Mediterranean region (EMRO) countries: a systematic review and meta-analysis. BMC Public Health. 2024;24(1):1395. doi: 10.1186/s12889-024-18816-z. - DOI - PMC - PubMed
    1. Yang H, Zhou R, Bai X, Guo M, Ruan G, Wang L, et al. Trend and geographic variation in incidence and prevalence of inflammatory bowel disease in regions across China: a nationwide employee study between 2013 and 2016. Front Med (Lausanne) 2022;9:900251. doi: 10.3389/fmed.2022.900251. - DOI - PMC - PubMed
    1. Luo H, Sun Y, Li Y, Lv H, Sheng L, Wang L, et al. Perceived stress and inappropriate coping behaviors associated with poorer quality of life and prognosis in patients with ulcerative colitis. J Psychosom Res. 2018;113:66–71. doi: 10.1016/j.jpsychores.2018.07.013. - DOI - PubMed

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