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. 2025 Apr 30:17:1183-1191.
doi: 10.2147/IJWH.S507648. eCollection 2025.

Determinants of Successful Vaginal Birth After Cesarean Section: A Retrospective Cohort Study in Southeast China

Ying-Ling Xiu  1 , Bing-Qing Lv  1
Affiliations

Determinants of Successful Vaginal Birth After Cesarean Section: A Retrospective Cohort Study in Southeast China

Ying-Ling Xiu et al. Int J Womens Health. .

Abstract

Objective: This study aimed to identify factors influencing the success of a trial of labor after cesarean section (TOLAC) and to evaluate associated maternal and neonatal outcomes.

Methods: A retrospective analysis was conducted on data from women with a prior cesarean section who underwent TOLAC at Fujian Maternity and Child Health Hospital in Southeast China between January 2016 and January 2018. Of the 1179 women who attempted TOLAC, 1038 achieved vaginal birth after cesarean (VBAC) while 141 experienced unsuccessful trials. Sociodemographic and clinical characteristics were compared between the successful and unsuccessful TOLAC groups using the t-test for normally distributed data, non-parametric tests for non-normally distributed data, and the χ2 test, corrected chi-square test, or Fisher's exact test for categorical variables, as appropriate. Logistic regression analysis was performed to identify factors independently associated with successful TOLAC, with the results expressed as Odds Ratios (ORs) and corresponding 95% Confidence Intervals (CIs).

Results: Multivariable logistic regression analysis revealed that maternal height (OR = 1.09, 95% CI = 1.05-1.14), abdominal circumference (OR = 0.95, 95% CI = 0.91-0.98), ultrasound-estimated fetal weight (OR = 0.99, 95% CI = 0.99-1.00), and history of vaginal delivery (OR = 9.62, 95% CI = 2.33-39.67) were independently associated with successful TOLAC. No significant differences were observed between the successful and unsuccessful TOLAC groups in terms of neonatal asphyxia, postpartum hemorrhage, placental abruption, or bladder injury.

Conclusion: Maternal height, abdominal circumference, ultrasound-estimated fetal weight, and history of vaginal delivery were identified as influential factors for VBAC success. Clinical evaluation of these factors may enhance the selection criteria for TOLAC candidates, potentially increasing VBAC rates and reducing cesarean section rates overall.

Keywords: pregnancy outcome; prior cesarean delivery; trial of labor after caesarean section; vaginal birth after caesarean section.

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Conflict of interest statement

The authors declare that they have no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Flowchart of the enrolled patients.
See this image and copyright information in PMC

References

    1. Li HT, Hellerstein S, Zhou YB, Liu JM, Blustein J. Trends in cesarean delivery rates in China, 2008-2018. JAMA. 2020;323(1):89–91. doi:10.1001/jama.2019.17595 - DOI - PMC - PubMed
    1. Sharma S, Dhakal I. Cesarean vs vaginal delivery: an institutional experience. JNMA J Nepal Med Assoc. 2018;56(209):535–539. doi:10.31729/jnma.3467 - DOI - PMC - PubMed
    1. Betran AP, Torloni MR, Zhang JJ, Gülmezoglu AM, WHO Working Group on Caesarean Section. WHO statement on caesarean section rates. BJOG. 2016;123(5):667–670. doi:10.1111/1471-0528.13526 - DOI - PMC - PubMed
    1. Ma RM, Duan T, Lao TT. VBAC should be encouraged as a means to reduce the caesarean section rate in China: FOR: VBAC reduces not only the caesarean section rate but also other associated issues. BJOG. 2016;123(Suppl 3):10. doi:10.1111/1471-0528.14291 - DOI - PubMed
    1. Zeng Y, Hesketh T. The effects of China’s universal two-child policy. Lancet. 2016;388(10054):1930–1938. doi:10.1016/S0140-6736(16)31405-2 - DOI - PMC - PubMed

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