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. 2025 May 5;35(9):R320-R322.
doi: 10.1016/j.cub.2025.03.068.

ER-to-lysosome-associated degradation

Affiliations

ER-to-lysosome-associated degradation

Maurizio Molinari. Curr Biol. .

Abstract

Maurizio Molinari introduces ER-to-lysosome-associated degradation - the autophagic and non-autophagic pathways that deliver ERAD-resistant misfolded proteins to the lysosome for degradation to maintain cellular proteostasis.

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Conflict of interest statement

Declaration of interests The author declares no competing interests.

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