Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 Apr 22:16:1576179.
doi: 10.3389/fpsyt.2025.1576179. eCollection 2025.

Case Report: The intersection of psychiatry and medicine: diagnostic and ethical insights from case studies

Affiliations
Case Reports

Case Report: The intersection of psychiatry and medicine: diagnostic and ethical insights from case studies

Francesco Monaco et al. Front Psychiatry. .

Abstract

The intersection of psychiatry and medicine presents unique diagnostic and ethical challenges, particularly for conditions involving significant brain-body interactions, such as psychosomatic, somatopsychic, and complex systemic disorders. This article explores the historical and contemporary issues in diagnosing such conditions, emphasizing the fragmentation of medical and psychiatric knowledge, biases in clinical guidelines, and the mismanagement of complex illnesses. Diagnostic errors often arise from insufficient integration between general medicine and psychiatry, compounded by the reliance on population-based guidelines that neglect individual patient needs. Misclassification of conditions like myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Lyme disease, and fibromyalgia as psychosomatic or psychogenic has led to stigmatization and delayed care. While these conditions are referenced as emblematic examples of misclassified and poorly understood disorders, the five clinical cases discussed in this article do not directly illustrate these diseases. Instead, they exemplify shared diagnostic and ethical dilemmas at the medicine-psychiatry interface, including uncertainty, fragmentation, and the risk of epistemic injustice. The article critically examines terms like medically unexplained symptoms and functional disorders, highlighting their limitations and potential for misuse. Case examples underscore the consequences of diagnostic inaccuracies and the urgent need for improved approaches. Ethical considerations are also explored, emphasizing respecting patient experiences, promoting individualized care, and acknowledging the inherent uncertainties in medical diagnosis. Advances in technologies such as brain imaging and molecular diagnostics offer hope for bridging the gap between psychiatry and medicine, enabling more accurate assessments and better patient outcomes. The article concludes by advocating comprehensive training at the medicine-psychiatry interface and a patient-centered approach that integrates clinical observation, research insights, and a nuanced understanding of mind-body dynamics.

Keywords: complex systemic disorders; diagnostic challenges; ethical implications; medicine-psychiatry interface; psychosomatic disorders; somatopsychic conditions.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

References

    1. Bradford A, Meyer AND, Khan S, Giardina TD, Singh H. Diagnostic error in mental health: a review. BMJ Qual Saf. (2024) 33:663–72. doi: 10.1136/bmjqs-2023-016996 - DOI - PMC - PubMed
    1. Hert M DE, Correll CU, Bobes J, Cetkovich-Bakmas M, Cohen D, Asai I, et al. . Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care. World Psychiatry. (2011) 10:52–77. doi: 10.1002/j.2051-5545.2011.tb00014.x - DOI - PMC - PubMed
    1. Plug I, van Dulmen S, Stommel W, Olde Hartman TC, Das E. Physicians’ and patients’ Interruptions in clinical practice: A quantitative analysis. Ann Fam Med. (2022) 20:423–9. doi: 10.1370/afm.2846 - DOI - PMC - PubMed
    1. Andreassen OA, Hindley GFL, Frei O, Smeland OB. New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications. World Psychiatry. (2023) 22:4–24. doi: 10.1002/wps.21034 - DOI - PMC - PubMed
    1. Deaton A, Cartwright N. Understanding and misunderstanding randomized controlled trials. Soc Sci Med. (2018) 210:2–21. doi: 10.1016/j.socscimed.2017.12.005 - DOI - PMC - PubMed

Publication types

LinkOut - more resources