doi: 10.1016/0022-4731(85)90238-9.
Testosterone and dihydrotestosterone levels in epididymis, vas deferens, seminal vesicle and preputial gland of mice after hCG injection
- PMID: 4033119
- DOI: 10.1016/0022-4731(85)90238-9
Item in Clipboard
Testosterone and dihydrotestosterone levels in epididymis, vas deferens, seminal vesicle and preputial gland of mice after hCG injection
J Steroid Biochem.
1985 Aug.
Abstract
Temporal changes of testosterone (T) and dihydrotestosterone (DHT) levels were measured by RIA in epididymis, vas deferens, seminal vesicle and preputial gland of adult male mice after a single injection of hCG. The response of circulating T to hCG stimulation was rapid and persisted over a period of 48 h. The temporal changes of androgen content of target organs paralleled the modifications of circulating T. In all organs the high androgen levels attained at 1 or 4 h plateaued until 24 h, decreased thereafter and returned to basal values at 72 h. The concentration of T by sex accessory organs was more accelerated by hCG injection than its conversion into DHT.
Similar articles
-
Testosterone and dihydrotestosterone levels in the epididymis, vas deferens and preputial gland of mice during sexual maturation.Int J Androl. 1985 Feb;8(1):44-57. doi: 10.1111/j.1365-2605.1985.tb00817.x. Int J Androl. 1985. PMID: 3997271
-
Regional differences in the testosterone to dihydrotestosterone ratio in the epididymis and vas deferens of adult mice.J Reprod Fertil. 1986 Mar;76(2):537-43. doi: 10.1530/jrf.0.0760537. J Reprod Fertil. 1986. PMID: 3701698
-
A comparative study of the conversion of testosterone to 17-beta-hydroxy-5-alpha-androstan-3-one (Dihydrotestosterone) by prostate and epididymis.J Clin Endocrinol Metab. 1969 Jul;29(7):970-7. doi: 10.1210/jcem-29-7-970. J Clin Endocrinol Metab. 1969. PMID: 5815723 No abstract available.
-
Prolactin influences upon androgen action in male accessory sex organs.Adv Sex Horm Res. 1976;2:425-70. Adv Sex Horm Res. 1976. PMID: 189591 Review.
-
Production and secretion of 5alpha-reduced testosterone (DHT) by male reproductive organs.J Steroid Biochem. 1975 Mar-Apr;6(3-4):337-9. doi: 10.1016/0022-4731(75)90152-1. J Steroid Biochem. 1975. PMID: 1102796 Review. No abstract available.
Cited by
-
Arrested spermatogenesis and evidence for DNA damage in PTIP mutant testes.Dev Biol. 2013 Jan 1;373(1):64-71. doi: 10.1016/j.ydbio.2012.10.006. Epub 2012 Oct 12. Dev Biol. 2013. PMID: 23063797 Free PMC article.
-
Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b5 in Leydig Cells.Mol Endocrinol. 2016 Apr;30(4):469-78. doi: 10.1210/me.2015-1282. Epub 2016 Mar 14. Mol Endocrinol. 2016. PMID: 26974035 Free PMC article.