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Case Reports
. 2025 Mar-Apr;39(2):99-103.

Osteomyelitis of the talus in infants following Bacillus Calmette-Guérin (BCG) vaccination

P Eamara  1 , S Kohan-Fortuna-Figueira  2 , C Halliburton  2 , J J Masquijo  1 , V Allende  1
Affiliations
  • PMID: 40335126
Free article
Case Reports

Osteomyelitis of the talus in infants following Bacillus Calmette-Guérin (BCG) vaccination

P Eamara et al. Acta Ortop Mex. 2025 Mar-Apr.
Free article

Abstract
in English, Spanish

Osteomyelitis caused by Bacillus Calmette-Guerin (BCG) is a rare complication of Mycobacterium bovis vaccination. Lesions are usually localized in the metaphysis or epiphysis of long bones, but rarely affect the foot. This report describes two cases of BCG osteomyelitis involving the talus in infants of 13 months and eight months old. BCG-osteomyelitis should be suspected in children under two years of age with insidious osteomyelitis, accompanied with characteristic imaging findings.

La osteomielitis causada por el bacilo de Calmette-Guérin (BCG) es una complicación poco frecuente de la vacunación con Mycobacterium bovis. Las lesiones suelen localizarse en la metáfisis o epífisis de los huesos largos, pero rara vez afectan el pie. En este informe se describen dos casos de osteomielitis por BCG que afectaban el astrágalo en lactantes de 13 y ocho meses de edad. La osteomielitis por BCG debe sospecharse en niños menores de dos años con osteomielitis insidiosa, acompañada de hallazgos característicos en las imágenes.

Keywords: BCG osteomyelitis; Mendelian susceptibility to mycobacterial diseases; Mycobacterium bovis; children.

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