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Case Reports
. 2025 Jan-Mar;15(1):60-62.
doi: 10.4103/ijabmr.ijabmr_363_24. Epub 2025 Jan 9.

A Rare Supraorbital Ridge Mass: The Chondroid Syringoma with Adipocytic Metaplasia

Anil Prasad  1 , Binod Kumar  2 , Sameer Kumar Mehta  3 , Minakshi Mishra  1
Affiliations
Case Reports

A Rare Supraorbital Ridge Mass: The Chondroid Syringoma with Adipocytic Metaplasia

Anil Prasad et al. Int J Appl Basic Med Res. 2025 Jan-Mar.

Abstract

Chondroid syringoma (CS) is a rare benign skin adnexal neoplasm. Its incidence is very low among all primary skin tumors. Diagnosing it clinically can be difficult as it closely resembles other benign salivary or adnexal neoplasms. Until now, only a few cases have been reported from the periorbital region. Clinically, it can be mistaken for epidermal cysts, but ectopic salivary glands are a close differential diagnosis. To diagnose it, a complete removal is usually required, followed by a histopathological examination. We present a unique case of a 45-year-old female patient with a CS in her right supraorbital ridge and review the pertinent literature.

Keywords: Adnexal neoplasm; chondroid syringoma; mixed tumor.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Small lump on the right supraorbital ridge
Figure 2
Figure 2
Microphotograph showing benign ductal and myoepithelial cells (blue arrow) in chondromyxoid stroma and adipocytic metaplasia (yellow arrow) (H and E, ×400)
Figure 3
Figure 3
IHC (a) Cytokeratin-positive ductal cells (b) p63 (c) S-100-positive myoepithelial cells (d) Ki-67 index low (5%)
See this image and copyright information in PMC

References

    1. Hirsch P, Helwig EB. Chondroid syringoma. Mixed tumor of skin, salivary gland type. Arch Dermatol. 1961;84:835–47. - PubMed
    1. Yavuzer R, Başterzi Y, Sari A, Bir F, Sezer C. Chondroid syringoma: A diagnosis more frequent than expected. Dermatol Surg. 2003;29:179–81. - PubMed
    1. Paraskevopoulos K, Cheva A, Koloutsos G, Matzarakis I, Vahtsevanos K. Chondroid syringoma of the medial canthus. Case Rep Otolaryngol. 2014;2014:158527. - PMC - PubMed
    1. Min KH, Byun JH, Lim JS, Lee HK, Lee WM, Joo JE. Chondroid syringoma on face. Arch Craniofac Surg. 2016;17:173–5. - PMC - PubMed
    1. Reddy PB, Nandini DB, Sreedevi R, Deepak BS. Benign chondroid syringoma affecting the upper lip: Report of a rare case and review of literature. J Oral Maxillofac Pathol. 2018;22:401–5. - PMC - PubMed

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