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Editorial
. 2025 Apr 10:10:20.
doi: 10.21037/tgh-24-121. eCollection 2025.

A new dawn in cancer immunotherapy: the promise of mutant KRAS-specific vaccines

Sheela Ruby Damle  1 , Venu Gopal Pillarisetty  2 , Rachael Ann Safyan  1   3 , Elena Gabriela Chiorean  1   3
Affiliations
Editorial

A new dawn in cancer immunotherapy: the promise of mutant KRAS-specific vaccines

Sheela Ruby Damle et al. Transl Gastroenterol Hepatol. .
No abstract available

Keywords: Cancer vaccine; KRAS; colorectal cancer (CRC); pancreatic ductal adenocarcinoma (PDA).

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tgh.amegroups.com/article/view/10.21037/tgh-24-121/coif). V.G.P. reports lab research funding from NGM, OncoResponse and Merck and payment from Sensei, Umoja and TriSalus. R.A.S. reports research funding (paid to the institution) by Verastem, Exelixis, Replimune as well as the V Foundation, and advisory board member for Ipsen, Guardant Health, and Agenus. E.G.C. reports advisory board role for Ipsen, Merus, Pfizer, BMS, Takeda, Regeneron, BPGBio, IGM Biosciences, G1 Therapeutics, Merck, Novartis, Astellas, and Foundation Medicine; and research funding, paid to the institution, by Lonza, AffiniT, Erasca, BMS, Novartis, Gilead, Merck, Roche, AADi, Boehringer-Ingelheim, Fibrogen, Cornerstone, Biosplice. The other author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Study design and treatment overview. Created with Biorender software. CA19-9, carbohydrate antigen 19-9; CEA, carcinoembryonic antigen; ctDNA, circulating tumor DNA; MRD, minimal residual disease; PBMC, peripheral blood mononuclear cells.
See this image and copyright information in PMC

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