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Comment
. 2025 May 8;388(6747):592-593.
doi: 10.1126/science.adx8688. Epub 2025 May 8.

The hunt for common tumor antigens

David A Tuveson  1
Affiliations
Comment

The hunt for common tumor antigens

David A Tuveson. Science. .

Abstract

Pancreatic cancer cells express cryptic peptides shared across patients that may be therapeutic targets.

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  • Pancreatic cancer-restricted cryptic antigens are targets for T cell recognition.
    Ely ZA, Kulstad ZJ, Gunaydin G, Addepalli S, Verzani EK, Casarrubios M, Clauser KR, Wang X, Lippincott IE, Louvet C, Schmitt T, Kapner KS, Agus MP, Hennessey CJ, Cleary JM, Hadrup SR, Klaeger S, Su J, Jaeger AM, Wolpin BM, Raghavan S, Smith EL, Greenberg PD, Aguirre AJ, Abelin JG, Carr SA, Jacks T, Freed-Pastor WA. Ely ZA, et al. Science. 2025 May 8;388(6747):eadk3487. doi: 10.1126/science.adk3487. Epub 2025 May 8. Science. 2025. PMID: 40339010 Free PMC article.

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