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. 2025 May 27;201(7):511-521.
doi: 10.1093/rpd/ncaf048.

Dose coefficients of ICRP adult reference voxel phantom for internal dosimetry of selected radiopharmaceuticals using Geant4/GATE simulation

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Dose coefficients of ICRP adult reference voxel phantom for internal dosimetry of selected radiopharmaceuticals using Geant4/GATE simulation

S Kaddouch et al. Radiat Prot Dosimetry. .

Abstract

One of the main objectives of this internal dosimetry research is the evaluation of the absorbed dose in the target organs. This aim can be achieved by combining the Monte Carlo method with a voxelized phantom in a numerical simulation platform. In internal dosimetry, Monte Carlo method is recognized as the most efficient method for absorbed dose calculation. Several Monte Carlo codes have been developed for this purpose. Geant4/GATE is one of the existing Monte Carlo codes. In this context, we have chosen to evaluate the absorbed dose of some radiopharmaceuticals using the International Commission on Radiological Protection adult reference voxel phantom and Geant4/GATE. First, the specific absorbed fractions were estimated for photon sources from 10 keV to 10 MeV. Then, absorbed doses were calculated for some radionuclides. Therefore, dose coefficients were determined for 20 target regions for each radionuclide. The results were compared with the literature.

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