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Editorial
. 2025 Apr 1;14(2):305-307.
doi: 10.21037/hbsn-2025-45. Epub 2025 Mar 21.

Recurrence beyond Milan criteria following liver resection for early-stage hepatocellular carcinoma: incidence, prediction and implications for treatment selection

Diamantis I Tsilimigras  1 , Ioannis Ntanasis-Stathopoulos  2 , Dimitrios Moris  3
Affiliations
Editorial

Recurrence beyond Milan criteria following liver resection for early-stage hepatocellular carcinoma: incidence, prediction and implications for treatment selection

Diamantis I Tsilimigras et al. Hepatobiliary Surg Nutr. .
No abstract available

Keywords: Milan criteria; Recurrence; early-stage; hepatocellular carcinoma (HCC); resection.

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://hbsn.amegroups.com/article/view/10.21037/hbsn-2025-45/coif). The authors have no conflicts of interest to declare.

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References

    1. Fuster-Anglada C, Mauro E, Ferrer-Fàbrega J, et al. Histological predictors of aggressive recurrence of hepatocellular carcinoma after liver resection. J Hepatol 2024;81:995-1004. 10.1016/j.jhep.2024.06.018 - DOI - PubMed
    1. Tsilimigras DI, Mehta R, Guglielmi A, et al. Recurrence beyond the Milan criteria after curative-intent resection of hepatocellular carcinoma: A novel tumor-burden based prediction model. J Surg Oncol 2020;122:955-63. 10.1002/jso.26091 - DOI - PubMed
    1. Pelizzaro F, Trevisani F, Simeon V, et al. Predictors of non-transplantable recurrence in hepatocellular carcinoma patients treated with frontline liver resection. Liver Int 2023;43:2762-75. 10.1111/liv.15719 - DOI - PubMed
    1. Kim M, Kim T, Lee HY, et al. Risk Factors for Beyond Milan Recurrence After Hepatic Resection for Single Hepatocellular Carcinoma No Larger Than 5 Centimeters. Liver Transpl 2021;27:1116-29. - PubMed
    1. Pawlik TM, Delman KA, Vauthey JN, et al. Tumor size predicts vascular invasion and histologic grade: Implications for selection of surgical treatment for hepatocellular carcinoma. Liver Transpl 2005;11:1086-92. - PubMed

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