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Review
. 2025 Jun;60(2):283-292.
doi: 10.1016/j.cnur.2025.01.006. Epub 2025 Feb 15.

Pharmacogenomics for Nurses

Affiliations
Review

Pharmacogenomics for Nurses

Dennis J Cheek et al. Nurs Clin North Am. 2025 Jun.

Abstract

In the new and evolving area of precision medicine, the nurse will not only have to rely on the 5 rights for medication administration but may also have to take into account the patient's genetic makeup. The 5 rights of medication administration have been incorporated into precision medicine, which includes pharmacogenetics-the specific gene and drug interaction- or more broadly, pharmacogenomics, which encompasses specific gene and drug interactions and other genetic and environmental factors. Pharmacogenomic testing is now available with specific guidelines to assist the prescriber with drug and dose selection to improve drug efficacy and reduce adverse drug reactions.

Keywords: Cardiovascular; Cytochrome P450; Mental health; Pain; Pharmacogenetics.

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