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Review
. 2025 May 11;17(5):e83877.
doi: 10.7759/cureus.83877. eCollection 2025 May.

Assessment and Decision-Making in Complex Limb Fracture Management

Affiliations
Review

Assessment and Decision-Making in Complex Limb Fracture Management

Daniel I Koshy et al. Cureus. .

Abstract

Complex limb fractures, particularly those resulting from high-energy trauma, pose significant challenges in orthopaedic trauma care due to the severity of bone and soft tissue damage, risk of infection, and the need for coordinated multidisciplinary management. This narrative review explores the comprehensive assessment and decision-making process involved in managing these injuries, including clinical evaluation, radiological imaging, and functional considerations. It critically examines factors influencing the choice between limb salvage and primary amputation, such as haemodynamic stability, injury severity, predictive scoring systems like the Mangled Extremity Severity Score (MESS), infection risk, functional outcomes, psychological well-being, and economic implications. Although limb salvage offers the potential to retain the native limb, it is often associated with prolonged recovery, multiple surgical interventions, and higher complication rates. Conversely, amputation may enable a more predictable and expedited return to function, particularly when extensive soft tissue loss or neurovascular compromise is present. The review emphasises that no single scoring system or algorithm can fully dictate management decisions, which must be individualised and guided by both clinical judgment and patient-centred goals. A multidisciplinary approach involving orthopaedic, vascular, and plastic surgeons, along with rehabilitation and mental health support, is essential to optimise outcomes. Future directions should focus on improving predictive tools and rehabilitation strategies to support evidence-based, holistic decision-making in complex limb trauma.

Keywords: complex fractures; complex lower limb trauma; limb salvage; orthopaedics; trauma.

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Conflict of interest statement

Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

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