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Case Reports
. 2025 May;15(5):80-84.
doi: 10.13107/jocr.2025.v15.i05.5564.

Phrenic Nerve Palsy in Anterior Cervical Discectomy and Fusion: Rare as Hen's Teeth

Affiliations
Case Reports

Phrenic Nerve Palsy in Anterior Cervical Discectomy and Fusion: Rare as Hen's Teeth

Aditya Gupta et al. J Orthop Case Rep. 2025 May.

Abstract

Introduction: Phrenic nerve palsy is a rare but potentially serious complication. The clinical presentation can vary from being asymptomatic to severe respiratory distress requiring mechanical complication. In the Anglophone literature, there is only a single case report of bilateral phrenic nerve injury as a complication following anterior cervical discectomy and fusion (ACDF).

Case report: This case report describes a 52-year-old female who developed right-sided phrenic nerve palsy after undergoing ACDF for cervical spine trauma. The patient had respiratory distress immediately after surgery and Ultrasonography and X-rays revealed Rt phrenic nerve palsy. To the best of our knowledge, this is the first case of unilateral phrenic nerve palsy after ACDF at the C5-C6 level.

Conclusion: Unilateral phrenic nerve palsy probably occurred as a complication of ACDF for cervical spine trauma. Phrenic nerve palsy should be kept in mind as a serious complication of spinal surgery.

Keywords: Phrenic nerve palsy; anterior cervical discectomy and fusion; cervical spine trauma; post-operative complication; respiratory distress.

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Conflict of interest statement

Conflict of Interest: Nil

Figures

Figure 1
Figure 1
AP and Lateral Radiographs of the cervical spine.
Figure 2
Figure 2
Sagittal CT scan showing grade 1 anterolisthesis of C5 over C6.
Figure 3
Figure 3
MRI showing cord contusion with upstream cord edema upto C2.
Figure 4
Figure 4
USG showing minimal movement with inspiration 5 days.
Figure 5
Figure 5
Chest X ray showing Right hemielevated diaphragm 1 week after surgery.

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References

    1. McAfee PC, Reah C, Gilder K, Eisermann L, Cunningham B. A meta-analysis of comparative outcomes following cervical arthroplasty or anterior cervical fusion:Results from 4 prospective multicenter randomized clinical trials and up to 1226 patients. Spine (Phila Pa 1976) 2012;37:943–52. - PubMed
    1. Timothy JY, Swong K, Park P. Complications of anterior cervical spine surgery:A systematic review of the literature. J Spine Surg. 2020;6:302–22. - PMC - PubMed
    1. Hitchon PW, Moritani T, Woodroffe RW, Abode-Iyamah K, Tecle NE, Noeller J, et al. C5 palsy following posterior decompression and instrumentation in cervical stenosis:Single center experience and review. Clin Neurol Neurosurg. 2018;174:29–35. - PubMed
    1. Jack A, Ramey WL, Dettori JR, Tymchak ZA, Oskouian RJ, Hart RA, et al. Factors associated with C5 palsy following cervical spine surgery:A systematic review. Global Spine J. 2019;9:881–94. - PMC - PubMed
    1. Fujibayashi S, Shikata J, Yoshitomi H, Tanaka C, Nakamura K, Nakamura T. Bilateral phrenic nerve palsy as a complication of anterior decompression and fusion for cervical ossification of the posterior longitudinal ligament. Spine (Phila Pa 1976) 2001;26:E281–6. - PubMed

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