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Observational Study
. 2025 May 9;104(19):e42138.
doi: 10.1097/MD.0000000000042138.

Application and effectiveness study of tripartite linkage nursing in prediabetes type 2 diabetes: A retrospective study

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Observational Study

Application and effectiveness study of tripartite linkage nursing in prediabetes type 2 diabetes: A retrospective study

Jiao Chen et al. Medicine (Baltimore). .

Abstract

This study aimed to evaluate the tripartite linkage nursing model's effectiveness in prediabetic patients at risk of type 2 diabetes mellitus, assessing its impact on glycemic control, metabolic outcomes, diabetes prevention, and treatment adherence. In this retrospective cohort study, 400 patients (2020-2022) were allocated via medical record review to control (standard care) and experimental groups (tripartite model integrating hospital-community-home management). Clinical parameters (fasting plasma glucose, 2-hour postprandial glucose, glycated hemoglobin, body mass index, lipid profiles, blood pressure) were monitored at baseline and 6-month intervals over 24 months, with diabetes incidence and adherence rates concurrently evaluated. The experimental group demonstrated superior outcomes: fasting plasma glucose (5.8 ± 0.4 vs 6.3 ± 0.5 mmol/L, P < .01), 2-hour postprandial glucose (7.2 ± 0.6 vs 8.1 ± 0.7 mmol/L, P < .01), and glycated hemoglobin (5.9 ± 0.3% vs 6.4 ± 0.4%, P < .01) showed significant improvements versus controls. Metabolic benefits included reduced body mass index (24.1 ± 2.1 vs 26.3 ± 2.4 kg/m²), optimized lipids (low-density lipoprotein cholesterol: 2.4 ± 0.3 vs 2.9 ± 0.4; triglycerides: 1.3 ± 0.2 vs 1.7 ± 0.3 mmol/L), and blood pressure control (124 ± 8/78 ± 5 vs 131 ± 10/83 ± 6 mm Hg, P < .05). Notably, diabetes incidence decreased by 50% (7.5% vs 15.0%, P = .008) with higher adherence rates (88.4% vs 72.6%, P < .001), confirming dual efficacy in biological and behavioral outcomes. The tripartite model effectively reduces glycemic levels, improves metabolic indicators, lowers diabetes incidence, and enhances compliance, demonstrating significant clinical value for early diabetes prevention and management.

Keywords: blood glucose control; incidence of diabetes; metabolic indicators; patient compliance; prediabetes type 2 diabetes; tripartite linkage nursing.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

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References

    1. Onuigwe FU, Ambi H, Uchechukwu NJ, et al. . Platelet dysfunction in diabetes mellitus. Elite J Med. 2024;2:1–7.
    1. Abolbaghaei A. Application of Circulating Large Extracellular Vesicles as Biomarkers in Type 1 Diabetes Mellitus and Pregnancy. Université d’Ottawa/University of Ottawa. 2023.
    1. Tan KX, Danquah MK, Jeevanandam J, Barhoum A. Development of Janus particles as potential drug delivery systems for diabetes treatment and antimicrobial applications. Pharmaceutics. 2023;15:423. - PMC - PubMed
    1. Li YY, Tong LP, Wu XD, Lin D, Lin Y, Lin X-Y. Analysis of influencing factors and interaction of body weight and disease outcome in patients with prediabetes. World J Diabetes. 2023;14:1551–61. - PMC - PubMed
    1. Gong D, Chen X, Yang L, et al. . From normal population to prediabetes and diabetes: study of influencing factors and prediction models. Front Endocrinol. 2023;14:1225696. - PMC - PubMed

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