. 2025 May 13;18(1):21.

doi: 10.1186/s13044-025-00229-8.

Factors linked to poor self-rated health in thyroid disorder patients: findings from LASI Wave-I

Pawan Kumar^#¹, Arunima Sen^#¹, Priyanshu Priyanshu², Mahalaqua Nazli Khatib^#³, R Roopashree⁴, Mandeep Kaur⁵, Manish Srivastava⁶, Amit Barwal⁷, G V Siva Prasad⁸, Pranchal Rajput⁹, Muhammed Shabil^{10

11}, Rukshar Syed¹², Gajendra Sharma¹³, Abhay M Gaidhane¹⁴, Diptismita Jena¹⁵, Ganesh Bushi^{16

17}, Rachana Mehta¹⁸, Amit Verma¹⁹, Hashem Abu Serhan²⁰, Ahmad Neyazi^{21

22}, Prakasini Satapathy^{23

24}

Affiliations

¹ Department of Community Medicine, School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
² Global Center for Evidence Synthesis, Chandigarh, India.
³ Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, Maharashtra, India.
⁴ Department of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India.
⁵ Department of Allied Healthcare and Sciences, Vivekananda Global University, Jaipur, Rajasthan, 303012, India.
⁶ Department of Endocrinology, NIMS University, Jaipur, Rajasthan, India.
⁷ Chandigarh Pharmacy College, Chandigarh Group of College, Jhanjeri, Mohali, 140307, Punjab, India.
⁸ Department of Chemistry, Raghu Engineering College, Visakhapatnam, 531162, Andhra Pradesh, India.
⁹ School of Applied and Life Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India.
¹⁰ University Center for Research and Development, Chandigarh University, Mohali, Punjab, India.
¹¹ Medical Laboratories Techniques Department, AL-Mustaqbal University, Hillah, Babil, 51001, Iraq.
¹² IES Institute of Pharmacy, IES University, Bhopal, 462044, Madhya Pradesh, India.
¹³ New Delhi Institute of Management, Delhi, India.
¹⁴ Global Health Academy, School of Epidemiology and Public Health, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education, Wardha, Maharashtra, India.
¹⁵ Center for Global Health Research, Saveetha Institute of Medical and Technical Sciences, Saveetha Medical College and Hospital, Saveetha University, Chennai, Tamil Nadu, India.
¹⁶ School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
¹⁷ University of Cyberjaya, Persiaran Bestari, Cyber 11, Selangor Darul Ehsan, Cyberjaya, 63000, Malaysia.
¹⁸ Clinical Microbiology, RDC, Manav Rachna International Institute of Research and Studies, Faridabad, 121004, Haryana, India.
¹⁹ Department of Medicine, Graphic Era Institute of Medical Sciences, Graphic Era (Deemed to be University, Clement Town, Dehradun, Uttarakhand, India.
²⁰ Department of Ophthalmology, Hamad Medical Corporation, Doha, Qatar.
²¹ Afghanistan Center for Epidemiological Studies, Herat, Afghanistan. neyazi.a@aces-af.org.
²² Faculty of Medicine, Ghalib University, Herat, Afghanistan. neyazi.a@aces-af.org.
²³ Centre of Research Impact and Outcome, Chitkara University, Rajpura, 140417, Punjab, India. prakasini.satapathy@gmail.com.
²⁴ Faculty of Data Science and Information Technology, INTI International University, Nilai, Malaysia. prakasini.satapathy@gmail.com.

^# Contributed equally.

PMID: 40355879
PMCID: PMC12070758
DOI: 10.1186/s13044-025-00229-8

Factors linked to poor self-rated health in thyroid disorder patients: findings from LASI Wave-I

Pawan Kumar et al. Thyroid Res. 2025.

. 2025 May 13;18(1):21.

doi: 10.1186/s13044-025-00229-8.

Authors

Affiliations

¹ Department of Community Medicine, School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
² Global Center for Evidence Synthesis, Chandigarh, India.
³ Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, Maharashtra, India.
⁴ Department of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India.
⁵ Department of Allied Healthcare and Sciences, Vivekananda Global University, Jaipur, Rajasthan, 303012, India.
⁶ Department of Endocrinology, NIMS University, Jaipur, Rajasthan, India.
⁷ Chandigarh Pharmacy College, Chandigarh Group of College, Jhanjeri, Mohali, 140307, Punjab, India.
⁸ Department of Chemistry, Raghu Engineering College, Visakhapatnam, 531162, Andhra Pradesh, India.
⁹ School of Applied and Life Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India.
¹⁰ University Center for Research and Development, Chandigarh University, Mohali, Punjab, India.
¹¹ Medical Laboratories Techniques Department, AL-Mustaqbal University, Hillah, Babil, 51001, Iraq.
¹² IES Institute of Pharmacy, IES University, Bhopal, 462044, Madhya Pradesh, India.
¹³ New Delhi Institute of Management, Delhi, India.
¹⁴ Global Health Academy, School of Epidemiology and Public Health, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education, Wardha, Maharashtra, India.
¹⁵ Center for Global Health Research, Saveetha Institute of Medical and Technical Sciences, Saveetha Medical College and Hospital, Saveetha University, Chennai, Tamil Nadu, India.
¹⁶ School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India.
¹⁷ University of Cyberjaya, Persiaran Bestari, Cyber 11, Selangor Darul Ehsan, Cyberjaya, 63000, Malaysia.
¹⁸ Clinical Microbiology, RDC, Manav Rachna International Institute of Research and Studies, Faridabad, 121004, Haryana, India.
¹⁹ Department of Medicine, Graphic Era Institute of Medical Sciences, Graphic Era (Deemed to be University, Clement Town, Dehradun, Uttarakhand, India.
²⁰ Department of Ophthalmology, Hamad Medical Corporation, Doha, Qatar.
²¹ Afghanistan Center for Epidemiological Studies, Herat, Afghanistan. neyazi.a@aces-af.org.
²² Faculty of Medicine, Ghalib University, Herat, Afghanistan. neyazi.a@aces-af.org.
²³ Centre of Research Impact and Outcome, Chitkara University, Rajpura, 140417, Punjab, India. prakasini.satapathy@gmail.com.
²⁴ Faculty of Data Science and Information Technology, INTI International University, Nilai, Malaysia. prakasini.satapathy@gmail.com.

^# Contributed equally.

PMID: 40355879
PMCID: PMC12070758
DOI: 10.1186/s13044-025-00229-8

Abstract

Background: Thyroid disorders affect the physical, behavioural, and psychological aspects of an individual, leading to poor self-rated health (SRH). Hence, we aimed to determine the prevalence of poor SRH and the factors associated with it among thyroid disorder patients.

Methods: This is an observational study consisting of 2336 thyroid disorder patients from LASI, 2017-19. Descriptive statistics were employed to calculate prevalence. The association between poor SRH and socio-demographic variables was evaluated using regression analysis, with results expressed as (AOR) and 95% CI.

Results: The findings showed poor self-rated health predictors among thyroid disorder patients, where 25% rated their health as poor. Significant predictors included older age, with patients aged ≥ 75 years having a higher likelihood of reporting poor health (aOR = 2.36, 95% CI = 1.32-4.22, p = 0.004), and rural residence (aOR = 1.34, 95% CI = 1.07-1.67, p = 0.011). Belonging to the OBC caste (aOR = 1.57, 95% CI = 1.23-2.00, p < 0.001) and practicing Christianity (aOR = 1.90, 95% CI = 1.25-2.89, p = 0.003) were also associated with increased odds of poor SRH. Previous employment (aOR = 1.65, 95% CI = 1.20-2.25, p = 0.002), co-morbidities (aOR = 2.59, 95% CI = 1.88-3.59, p < 0.001), and lower education levels (aOR = 1.50, 95% CI = 1.06-2.13, p = 0.022) were significant. Limitations in activities of daily living and instrumental activities of daily living were linked to poorer health outcomes (aOR = 1.76, 95% CI = 1.33-2.31, p < 0.001; IADL: aOR = 1.41, 95% CI = 1.11-1.79, p = 0.004). Depression (aOR = 1.84, 95% CI = 1.32-2.56, p < 0.001) and healthcare utilization in the past year (aOR = 1.86, 95% CI = 1.33-2.58, p < 0.001) also predicted poor SRH, with most healthcare utilization (79.8%) occurring in private facilities.

Conclusion: The study highlights a high prevalence of poor SRH among patients, with significant associations observed with age, residence, comorbidity, and healthcare utilization. Targeted interventions focusing on healthcare access, physical activity, and mental health support are crucial to improve SRH.

Keywords: Goitre; Good Health and Well-being; Hashimoto's Thyroiditis; Healthcare utilization, thyroid cancer; Hyperthyroidism; Hypothyroidism.

PubMed Disclaimer

Conflict of interest statement

Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: Not applicable. Human ethics and consent to participate: Not applicable. Clinical trial number: Not applicable. Competing interests: The authors declare no competing interests.

Figures

**Fig. 1**
Type of healthcare provider consulted by patients with thyroid disorders, India, LASI wave 1, 2017-2019 (N=1910)

See this image and copyright information in PMC

References

1. Medicine JH. Thyroid Disorders: John Hopkins Medicine; 2024 [Available from: https://www.hopkinsmedicine.org/health/conditions-and-diseases/disorders...
1. Vanderpump MPJ. Epidemiology of thyroid disorders. In: Luster M, Duntas LH, Wartofsky L, editors. The thyroid and its diseases: a Comprehensive Guide for the Clinician. Cham: Springer International Publishing; 2019. pp. 75–85.
1. Taylor PN, Albrecht D, Scholz A, Gutierrez-Buey G, Lazarus JH, Dayan CM, Okosieme OE. Global epidemiology of hyperthyroidism and hypothyroidism. Nat Reviews Endocrinol. 2018;14(5):301–16. - PubMed
1. Bianchi GP, Zaccheroni V, Solaroli E, Vescini F, Cerutti R, Zoli M, Marchesini G. Health-related quality of life in patients with thyroid disorders. Qual Life Res. 2004;13(1):45–54. - PubMed
1. Leso V, Vetrani I, De Cicco L, Cardelia A, Fontana L, Buonocore G, Iavicoli I. The impact of thyroid diseases on the Working Life of patients: a systematic review. Int J Environ Res Public Health [Internet]. 2020; 17(12). - PMC - PubMed

LinkOut - more resources

Full Text Sources
- BioMed Central
- PubMed Central
Miscellaneous
- NCI CPTAC Assay Portal

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Factors linked to poor self-rated health in thyroid disorder patients: findings from LASI Wave-I

Affiliations

Factors linked to poor self-rated health in thyroid disorder patients: findings from LASI Wave-I

Authors

Affiliations

Abstract

Conflict of interest statement

Figures

Similar articles

References

LinkOut - more resources

Full Text Sources

Miscellaneous

Abstract

Conflict of interest statement

Figures

Similar articles

References

Related information

LinkOut - more resources

Full Text Sources

Miscellaneous