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Review
. 2025 May 13;14(1):42.
doi: 10.1007/s13679-025-00630-2.

Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of Dietetics and Clinical Nutrition (ADI), the Italian Society of Dermatology and Sexually Transmitted Diseases (SIDeMaST), the Italian Society of Nutraceuticals (SINut), Club Ketodiets and Nutraceuticals "KetoNut-SINut" and the Italian Society of Endocrinology (SIE), Club Nutrition, Hormones and Metabolism

Luigi Barrea  1 , Ludovica Verde  2   3 , Giuseppe Annunziata  4 , Emiliano Antiga  5 , Elisabetta Camajani  6   7 , Massimiliano Caprio  6   7 , Maria Grazia Carbonelli  8 , Augusto Carducci  9 , Edda Cava  8 , Giorgia Di Marco  10 , Davide Grassi  9 , Stefania Guida  10 , Barbara Martinelli  11 , Angelo Valerio Marzano  12   13 , Chiara Moltrasio  12 , Massimiliano Petrelli  14 , Francesca Prignano  15 , Franco Rongioletti  10 , Silvia Savastano  16   17 , Barbara Paolini  18 , Carmela Bagnato  19 , Giuseppe Argenziano  20 , Arrigo Francesco Giuseppe Cicero  21   22 , Annamaria Colao  16   17   23 , Diego Ferone  24 , Gianluca Aimaretti  25 , Giovanna Muscogiuri  26   27   28
Affiliations
Review

Medical Nutrition Therapy in Dermatological Diseases: A Joint Consensus Statement of the Italian Association of Dietetics and Clinical Nutrition (ADI), the Italian Society of Dermatology and Sexually Transmitted Diseases (SIDeMaST), the Italian Society of Nutraceuticals (SINut), Club Ketodiets and Nutraceuticals "KetoNut-SINut" and the Italian Society of Endocrinology (SIE), Club Nutrition, Hormones and Metabolism

Luigi Barrea et al. Curr Obes Rep. .

Abstract

Dermatological diseases such as acne, hidradenitis suppurativa (HS), and psoriasis are driven by chronic inflammation and oxidative stress. Emerging evidence highlights the role of nutrition in modulating these conditions, particularly through dietary patterns rich in antioxidants, polyphenols, and unsaturated fatty acids. RECENT FINDINGS: The Mediterranean diet (MedDiet) has demonstrated potential benefits due to its anti-inflammatory and immunomodulatory effects, while very low-energy ketogenic therapy (VLEKT) has shown promise in rapidly improving disease severity. Specific nutrients, including omega-3 fatty acids, probiotics, and micronutrients, may further contribute to disease management. However, the current literature is limited by small-scale studies and the lack of standardized dietary guidelines. PURPOSE OF REVIEW: This Consensus Statement, developed collaboratively by the Italian Association of Dietetics and Clinical Nutrition (ADI), the Italian Society of Dermatology and Sexually Transmitted Diseases (SIDeMaST), the Italian Society of Nutraceuticals (SINut), Club Ketodiets and Nutraceuticals "KetoNut-SINut" and the Italian Society of Endocrinology (SIE), Club Nutrition, Hormones and Metabolism, aimed to establish an evidence-based framework for medical nutrition therapy (MNT) of the most common inflammatory skin diseases, including acne, HS and psoriasis.

Keywords: Acne; Diet; Hidradenitis suppurativa; Ketogenic diet; Medical nutrition therapy; Mediterranean diet; Nutrition; Obesity; Psoriasis; VLEKT.

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Conflict of interest statement

Declarations. Human and Animal Rights and Informed Consent: This article does not contain any studies with human or animal subjects performed by any of the authors. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Pathophysiology and role of the MedDiet and ketogenic diet in acne disease, summarizes the pathophysiology and role of the Mediterranean and ketogenic diets in acne disease. IGF- 1, Insulin-Like Growth Factor 1; C., Cutibacterium; MedDiet, Mediterranean Diet; KD, ketogenic diet
Fig. 2
Fig. 2
Pathophysiology and role of the MedDiet and ketogenic diet in HS disease, summarizes the pathophysiology and role of the Mediterranean and ketogenic diets in HS disease. TNF-α, Tumor Necrosis Factor Alpha; IL, Interleukin; MedDiet, Mediterranean Diet; KD, ketogenic diet
Fig. 3
Fig. 3
Pathophysiology and role of the MedDiet and ketogenic diet in psoriasis disease, summarizes the pathophysiology and role of the Mediterranean and ketogenic diets in psoriasis disease, IL, Interleukin; MedDiet, Mediterranean Diet; KD, ketogenic diet
Fig. 4
Fig. 4
Consensus statement of the ADI, SIDeMaST, SINut, and SIE. The most common inflammatory skin diseases, including acne, HS, and psoriasis are influenced by metabolic and dietary factors, highlighting the need for an integrated approach to management. Nutritional strategies, including the MedDiet and VLEKT, offers promising adjunctive therapies by reducing systemic inflammation and improving clinical outcomes. ADI, Italian Association of Dietetics and Clinical Nutrition; SIDeMaST, Italian Society of Dermatology and Sexually Transmitted Diseases; SIE, Italian Society of Endocrinology; SINut, Italian Society of Nutraceuticals; VLEKT, Very Low-Energy Ketogenic Therapy
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