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Review
. 2025 Oct;37(10).
doi: 10.25270/jic/25.00089.

Artificial intelligence for chronic total occlusion percutaneous coronary interventions

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Free article
Review

Artificial intelligence for chronic total occlusion percutaneous coronary interventions

Athanasios Rempakos et al. J Invasive Cardiol. 2025 Oct.
Free article

Abstract

Artificial intelligence (AI) has become pivotal in advancing medical care, particularly in interventional cardiology. Recent AI developments have proven effective in guiding advanced procedures and complex decisions. The authors review the latest AI-based innovations in the diagnosis of chronic total occlusions (CTO) and in determining the probability of success of CTO percutaneous coronary intervention (PCI). Neural networks and deep learning strategies were the most commonly used algorithms, and the models were trained and deployed using a variety of data types, such as clinical parameters and imaging. AI holds great promise in facilitating CTO PCI.

Keywords: CTO-PCI; artificial intelligence; chronic total occlusion; percutaneous coronary intervention.

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