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. 2025 Oct;125(10):944-959.
doi: 10.1055/a-2595-1811. Epub 2025 May 13.

Consensus on the Management of the Clinical Challenges of Venous Thromboembolism in Special Situations

Cristina Marzo  1 , Teresa Solanich  2 , Dolors Tassies  3 , Elena Pina  4 , Maite Antonio Rebollo  5 , Enrique Gallardo  6   7 , Sonia Serradell  8 , Marta Merino  9 , Marina Carrasco  10 , Albert Tugues  11
Affiliations

Consensus on the Management of the Clinical Challenges of Venous Thromboembolism in Special Situations

Cristina Marzo et al. Thromb Haemost. 2025 Oct.

Abstract

Venous thromboembolism (VTE) can present different challenging situations for which high-quality evidence to guide optimal preventive and therapeutic management is lacking and for which clinical practice guidelines have not established solid recommendations. The aim of this article is to achieve consensus on a proposal of action for the clinical management of complex, clinically relevant situations with a low level of evidence which generate great uncertainty-the duration of VTE treatment and the role of thrombus recanalization, the prevention of VTE within the context of pregnancy, management of anticoagulant treatment in patients with VTE and special characteristics, such as renal insufficiency and obesity, the therapeutic management of pluripathological and polymedicated older patients with VTE, and finally, primary ambulatory thromboembolic prevention in cancer patients. This consensus article arose from a collaboration of experts in VTE from different medical specialties.

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Conflict of interest statement

None declared.

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