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Case Reports
. 2025 May 5:2025:8840308.
doi: 10.1155/crnm/8840308. eCollection 2025.

Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review

Emily Grew  1 , Garrett Gianneschi  2 , Janet Elgallab  2
Affiliations
Case Reports

Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review

Emily Grew et al. Case Rep Neurol Med. .

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) following viral infections and influenza vaccination has been well documented. However, there have been no confirmed natural influenza A infections leading to development of CIDP. Therefore, we present the case of a 6-year-old male who developed CIDP following a confirmed influenza A infection. Initially presenting with typical flu-like symptoms, the patient experienced a gradual onset of gait instability and leg weakness approximately 1 month later. Despite initial improvement with intravenous immunoglobulin therapy following a diagnosis of Guillain-Barré syndrome, his symptoms relapsed, including lower extremity weakness, incontinence, and sensory loss. Electromyography confirmed a demyelinating polyneuropathy, leading to a diagnosis of CIDP.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Timeline of events.
Figure 2
Figure 2
Clockwise from top left: Normal Axial T1, T2 FSE, Diffusion Weighted Imagine, and T2 FLAIR.
See this image and copyright information in PMC

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