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Editorial
. 2025 Apr 7;16(5):717-718.
doi: 10.1021/acsmedchemlett.5c00158. eCollection 2025 May 8.

Novel Azaindole Compounds as Phosphodiesterase 4B Inhibitors for Treating Immune-Inflammatory Diseases or Disorders

Zhendong Song  1 , Steven H Liang  1
Affiliations
Editorial

Novel Azaindole Compounds as Phosphodiesterase 4B Inhibitors for Treating Immune-Inflammatory Diseases or Disorders

Zhendong Song et al. ACS Med Chem Lett. .

Abstract

This application reveals a novel series of azaindole compounds identified as phosphodiesterase 4B (PDE4B) inhibitors. The chemical synthesis, enzymatic inhibitory activity against PDE4B, selectivity over PDE4D, and pharmaceutical compositions are disclosed.

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Conflict of interest statement

The authors declare no competing financial interest.

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