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Review

LIVER DISEASE

In: Guidelines for the Management of Transfusion-Dependent β-Thalassaemia (TDT) [Internet]. 5th edition. Nicosia, Cyprus: Thalassaemia International Federation; 2025. Chapter 5.
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Review

LIVER DISEASE

Alessandra Mangia et al.
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No abstract available

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Conflict of interest statement

AM has served as speaker for Bristol Myers Squibb, Gilead Sciences, Janssen, and MSD. NP has served as speaker for Gilead Sciences, AlfaSigma, Advanz Pharma, Novo Nordisk, and Gore. AA reports grant and research support from AbbVie and Gilead Sciences; being on advisory boards for AbbVie, Gilead Sciences, MSD, Mylan, Intercept, Sobi, and Takeda. The remaining authors have no competing interests to disclose. All competing interests are outside the present work.

References

    1. GBD 2021 Diseases and Injuries Collaborators Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403(10440):2133–2161. - PMC - PubMed
    1. Musallam KM, Vitrano A, Meloni A, Pollina SA, Karimi M, El-Beshlawy A, Hajipour M, Di Marco V, Ansari SH, Filosa A, Ricchi P, Ceci A, Daar S, Vlachaki E, Singer ST, Naserullah ZA, Pepe A, Scondotto S, Dardanoni G, Bonifazi F, Sankaran VG, Vichinsky E, Taher AT, Maggio A Survival and causes of death in 2,033 patients with non-transfusion-dependent beta-thalassemia. Haematologica. 2021;106(9):2489–2492. - PMC - PubMed
    1. Voskaridou E, Kattamis A, Fragodimitri C, Kourakli A, Chalkia P, Diamantidis M, Vlachaki E, Drosou M, Lafioniatis S, Maragkos K, Petropoulou F, Eftihiadis E, Economou M, Klironomos E, Koutsouka F, Nestora K, Tzoumari I, Papageorgiou O, Basileiadi A, Lafiatis I, Dimitriadou E, Kalpaka A, Kalkana C, Xanthopoulidis G, Adamopoulos I, Kaiafas P, Mpitzioni A, Goula A, Kontonis I, Alepi C, Anastasiadis A, Papadopoulou M, Maili P, Dionisopoulou D, Tsirka A, Makis A, Kostaridou S, Politou M, Papassotiriou I, Greek Haemoglobinopathies Study G National registry of hemoglobinopathies in Greece: updated demographics, current trends in affected births, and causes of mortality. Ann Hematol. 2019;98(1):55–66. - PubMed
    1. Forni GL, Gianesin B, Musallam KM, Longo F, Rosso R, Lisi R, Gamberini MR, Pinto VM, Graziadei G, Vitucci A, Bonetti F, Musto P, Piga A, Cappellini MD, Borgna-Pignatti C, Webthal p Overall and complication-free survival in a large cohort of patients with beta-thalassemia major followed over 50 years. Am J Hematol. 2023;98(3):381387. - PubMed
    1. Gines P, Krag A, Abraldes JG, Sola E, Fabrellas N, Kamath PS Liver cirrhosis. Lancet. 2021;398(10308):1359–1376. - PubMed

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