Review

FERTILITY AND PREGNANCY

Marina Baldini¹, Maddalena Casale², Yi Li³, Farzana Sayani^{4

5}, James Smith³, Evangelia Vlachodimitropoulou⁶, Sylvia Titi Singer⁷

A.T. Taher¹, D. Farmakis², J.B. Porter³, M.D. Cappellini⁴, K.M. Musallam⁵

, editors.

In: Guidelines for the Management of Transfusion-Dependent β-Thalassaemia (TDT) [Internet]. 5th edition. Nicosia, Cyprus: Thalassaemia International Federation; 2025. Chapter 7.

Affiliations

¹ Unit of Medicine and Metabolic Disease, Department of Internal Medicine, IRCCS Fondazione Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
² Centre of Paediatric Haematology and Oncology, Department of Woman, Child and General and Specialised Surgery, University of Campania Luigi Vanvitelli, Naples, Italy
³ Department of Urology and Center for Reproductive Sciences, University of California San Francisco (UCSF), San Francisco, CA, USA
⁴ Red Blood Cell Disorders Program, Division of Medical Oncology and Haematology, Department of Medicine, University Health Network, University of Toronto, Toronto, Canada
⁵ Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
⁶ Department of Hematology/Oncology, University of California San Francisco (UCSF) Benioff Children’s Hospital Oakland, Oakland, CA, USA
⁷ Department of Obstetrics and Gynaecology, King’s College Hospital, London, United Kingdom

Book Affiliations

¹ Professor of Internal Medicine, Hematology & Oncology; Associate VP for Academic Centers, Development and External Affairs; Director, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut, Lebanon
² Associate Professor, Department of Cardiology, Athens University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece
³ Professor of Haematology (Emeritus) and Consultant Haematologist, University College London Hospitals, London, United Kingdom
⁴ Professor of Medicine, Unit of Medicine and Metabolic Disease, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
⁵ Group Chief Research Officer (Burjeel Holdings) and Founding Director, Center for Research on Rare Blood Disorders (CR-RBD), Burjeel Medical City, Abu Dhabi, United Arab Emirates; Adjunct Professor, Department of Public Health & Epidemiology, Khalifa University, Abu Dhabi, United Arab Emirates; Adjunct Professor, Division of Hematology/Oncology, Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA

PMID: 40367267
Bookshelf ID: NBK614246

Free Books & Documents

Review

FERTILITY AND PREGNANCY

Marina Baldini et al.

Free Books & Documents

In: Guidelines for the Management of Transfusion-Dependent β-Thalassaemia (TDT) [Internet]. 5th edition. Nicosia, Cyprus: Thalassaemia International Federation; 2025. Chapter 7.

Authors

Marina Baldini¹, Maddalena Casale², Yi Li³, Farzana Sayani^{4

5}, James Smith³, Evangelia Vlachodimitropoulou⁶, Sylvia Titi Singer⁷

Book Editors

A.T. Taher¹, D. Farmakis², J.B. Porter³, M.D. Cappellini⁴, K.M. Musallam⁵

Affiliations

¹ Unit of Medicine and Metabolic Disease, Department of Internal Medicine, IRCCS Fondazione Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
² Centre of Paediatric Haematology and Oncology, Department of Woman, Child and General and Specialised Surgery, University of Campania Luigi Vanvitelli, Naples, Italy
³ Department of Urology and Center for Reproductive Sciences, University of California San Francisco (UCSF), San Francisco, CA, USA
⁴ Red Blood Cell Disorders Program, Division of Medical Oncology and Haematology, Department of Medicine, University Health Network, University of Toronto, Toronto, Canada
⁵ Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
⁶ Department of Hematology/Oncology, University of California San Francisco (UCSF) Benioff Children’s Hospital Oakland, Oakland, CA, USA
⁷ Department of Obstetrics and Gynaecology, King’s College Hospital, London, United Kingdom

Book Affiliations

¹ Professor of Internal Medicine, Hematology & Oncology; Associate VP for Academic Centers, Development and External Affairs; Director, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut, Lebanon
² Associate Professor, Department of Cardiology, Athens University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece
³ Professor of Haematology (Emeritus) and Consultant Haematologist, University College London Hospitals, London, United Kingdom
⁴ Professor of Medicine, Unit of Medicine and Metabolic Disease, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
⁵ Group Chief Research Officer (Burjeel Holdings) and Founding Director, Center for Research on Rare Blood Disorders (CR-RBD), Burjeel Medical City, Abu Dhabi, United Arab Emirates; Adjunct Professor, Department of Public Health & Epidemiology, Khalifa University, Abu Dhabi, United Arab Emirates; Adjunct Professor, Division of Hematology/Oncology, Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA

PMID: 40367267
Bookshelf ID: NBK614246

No abstract available

PubMed Disclaimer

Conflict of interest statement

None to disclose.

Sections

References

1. Sayani FA, Singer ST, Carlberg KT, Vichinsky EP Fertility and Pregnancy in Women with TransfusionDependent Thalassemia. Hematol Oncol Clin North Am. 2023;37(2):393–411. - PubMed
1. Uysal A, Alkan G, Kurtoglu A, Erol O, Kurtoglu E Diminished ovarian reserve in women with transfusiondependent beta-thalassemia major: Is iron gonadotoxic? Eur J Obstet Gynecol Reprod Biol. 2017;216:69–73. - PubMed
1. Borgna-Pignatti C, Gamberini MR Complications of thalassemia major and their treatment. Expert Rev Hematol. 2011;4(3):353–366. - PubMed
1. Talaulikar VS, Bajoria R, Ehidiamhen AJ, Mujawar E, Chatterjee R A 10-year longitudinal study of evaluation of ovarian reserve in women with transfusion-dependent beta thalassaemia major. Eur J Obstet Gynecol Reprod Biol. 2019;238:38–43. - PubMed
1. Mensi L, Borroni R, Reschini M, Cassinerio E, Vegetti W, Baldini M, Cappellini MD, Somigliana E Oocyte quality in women with thalassaemia major: insights from IVF cycles. Eur J Obstet Gynecol Reprod Biol X. 2019;3:100048. - PMC - PubMed

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FERTILITY AND PREGNANCY

Affiliations

Book Affiliations

FERTILITY AND PREGNANCY

Authors

Book Editors

Affiliations

Book Affiliations

Conflict of interest statement

Sections

References

Publication types

LinkOut - more resources

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