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. 2025 Jun;51(3):250-261.
doi: 10.1177/26350106251336311. Epub 2025 May 14.

Chronic Illness Self-Management Latent Profiles in Individuals With Comorbid Type 2 Diabetes and Hypertension

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Chronic Illness Self-Management Latent Profiles in Individuals With Comorbid Type 2 Diabetes and Hypertension

Donghwan Lee et al. Sci Diabetes Self Manag Care. 2025 Jun.

Abstract

PurposeThe purpose of the study was to identify chronic illness self-management latent profiles based on health literacy, disease knowledge, self-efficacy, disease distress, perceived self-care, and medication use among individuals with type 2 diabetes and hypertension.MethodsThis cross-sectional study utilized baseline data from 220 participants in the EXTEND trial. Latent profile analysis was employed to identify distinct chronic illness self-management profiles based on attributes such as health literacy, disease knowledge, self-efficacy, disease distress, perceived self-care, and medication use. Sociodemographic and clinical data were analyzed to explore associations with these profiles.ResultsThree profiles were identified: "high distress" (18.1%), characterized by high disease distress and a high medication use score, indicating greater inconsistency in medication-taking behaviors; "high health knowledge" (38.6%), with high health literacy and disease knowledge; and "high self-efficacy" (43.3%), exhibiting high self-efficacy and perceived self-care. Significant differences in A1C levels were observed across profiles, with the high distress group showing the highest A1C levels. Racial identity and socioeconomic factors were significantly associated with profile membership.DiscussionThis study underscores the complexity of chronic illness self-management in individuals with comorbid diabetes and hypertension. Tailored, multifaceted interventions addressing the unique challenges individuals face in managing their illnesses are crucial for improving clinical outcomes and promoting health equity.

Trial registration: ClinicalTrials.gov NCT05120544.

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Conflict of interest statement

Declaration of Conflicting InterestsThe authors have no conflicts of interest to report.

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References

    1. Centers for Disease Control and Prevention. National diabetes statistics report. 2023. Accessed September 11, 2024. https://www.cdc.gov/diabetes/data/statistics-report/index.html
    1. Petrie JR, Guzik TJ, Touyz RM. Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms. Can J Cardiol. 2018;34(5):575–584. doi: 10.1016/j.cjca.2017.12.005 - DOI - PMC - PubMed
    1. Tomic D, Shaw JE, Magliano DJ. The burden and risks of emerging complications of diabetes mellitus. Nat Rev Endocrinol. 2022;18(9):525–539. doi: 10.1038/s41574-022-00690-7 - DOI - PMC - PubMed
    1. Parker ED, Lin J, Mahoney T, et al. Economic costs of diabetes in the U.S. in 2022. Diabetes Care. 2024;47(1):26–43. doi: 10.2337/dci23-0085 - DOI - PubMed
    1. Nowakowska M, Zghebi SS, Ashcroft DM, et al. The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort. BMC Med. 2019;17:145. doi: 10.1186/s12916-019-1373-y - DOI - PMC - PubMed

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