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Editorial
. 2025 Jun 24;43(7):sxaf031.
doi: 10.1093/stmcls/sxaf031.

In reply to Letter to the Editor from Paudel: Comment on "Changes in iPSC-Astrocyte Morphology Reflect Alzheimer's Disease Patient Clinical Markers"

Noel J Buckley  1   2 , Helen A Rowland  1   2
Affiliations
Editorial

In reply to Letter to the Editor from Paudel: Comment on "Changes in iPSC-Astrocyte Morphology Reflect Alzheimer's Disease Patient Clinical Markers"

Noel J Buckley et al. Stem Cells. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

None declared.

Comment in

Comment on

  • Changes in iPSC-astrocyte morphology reflect Alzheimer's disease patient clinical markers.
    Rowland HA, Miller G, Liu Q, Li S, Sharp NR, Ng B, Wei T, Arunasalam K, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Kocagoncu E, Lawson J, Malhotra P, Ridha BH, Rowe JB, Thomas AJ, Zamboni G, Zetterberg H, Cader MZ, Wade-Martins R, Lovestone S, Nevado-Holgado A, Kormilitzin A, Buckley NJ. Rowland HA, et al. Stem Cells. 2025 Mar 10;43(3):sxae085. doi: 10.1093/stmcls/sxae085. Stem Cells. 2025. PMID: 39704342 Free PMC article.

References

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    1. Muratore CR, Rice HC, Srikanth P, et al. The familial Alzheimer’s disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons. Hum Mol Genet. 2014;23:3523-3536. https://doi.org/ 10.1093/hmg/ddu064 - DOI - PMC - PubMed
    1. Israel MA, Yuan SH, Bardy C, et al. Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells. Nature. 2012;482:216-220. https://doi.org/ 10.1038/nature10821 - DOI - PMC - PubMed
    1. Sproul AA, Jacob S, Pre D, et al. Characterization and molecular profiling of PSEN1 familial Alzheimer’s disease iPSC-derived neural progenitors. PLoS One. 2014;9:e84547. https://doi.org/ 10.1371/journal.pone.0084547 - DOI - PMC - PubMed
    1. Ochalek A, Mihalik B, Avci HX, et al. Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation. Alzheimers Res Ther. 2017;9:90. https://doi.org/ 10.1186/s13195-017-0317-z - DOI - PMC - PubMed