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Review
. 2025 Jul 30;29(2):367-377.
doi: 10.5935/1518-0557.20250006.

Exploration of Herbal Medicinal Plants and Formulations Available for the Treatment of PCOS: A review

Affiliations
Review

Exploration of Herbal Medicinal Plants and Formulations Available for the Treatment of PCOS: A review

Arjoo Babhare et al. JBRA Assist Reprod. .

Abstract

Polycystic ovarian syndrome (PCOS) is a heterogeneous endocrine disorder with the underlying consequence of ovarian cysts, anovulation, and endocrine variation affecting women. According to the World Health Organization (WHO) estimation over 116 million women (3.4%) are affected by PCOS worldwide. It is typified by polycystic ovaries, hyperandrogenism, and ovulatory dysfunction. Pharmacological interventions that treat symptoms but may have fewer side effects are frequently used in conventional treatments. As a result, interest in herbal medicinal plants and formulations as additional or alternative PCOS therapies is developing. This review explores the safety and efficacy of various herbal remedies traditionally used in the management of PCOS. Each of the herbs mentioned in this review offers unique benefits. This review gives a comprehensive idea about PCOS, its causes and symptoms. It also explores formulations like capsules, tablets, syrups, and nano drug delivery system medicines for PCOS. According to studies, these herbal medicines can improve insulin resistance, lower testosterone levels and restore menstrual regularity while causing fewer negative effects than conventional therapy.

Keywords: formulations; herbal plants; polycystic ovary syndrome; treatment.

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Figures

Figure 1
Figure 1
Normal and Polycystic ovary.
Figure 2
Figure 2
Pathophysiology of PCOS.
Figure 3
Figure 3
Clinical manifestations with PCOS.
Figure 4
Figure 4
Global burden of PCOS (Knochenhauer et al., 1998).
Figure 5
Figure 5
Herbs used in the treatment of PCOS.

References

    1. Agarwal A, Deepinder F, Cocuzza M, Short RA, Evenson DP. Effect of vaginal lubricants on sperm motility and chromatin integrity: a prospective comparative study. Fertil Steril. 2008;89:375–379. doi: 10.1016/j.fertnstert.2007.02.050. . - DOI - PubMed
    1. Andhalkar S, Chaware V, Redasani V. A. Review on Medicinal Plants of Natural Origin for Treatment of Polycystic Ovarian Syndrome (PCOS) Asian J Pharm Res Dev. 2021;9:76–81. doi: 10.22270/ajprd.v9i3.949. - DOI
    1. Armanini D, Mattarello MJ, Fiore C, Bonanni G, Scaroni C, Sartorato P, Palermo M. Licorice reduces serum testosterone in healthy women. Steroids. 2004;69:763–766. doi: 10.1016/j.steroids.2004.09.005. - DOI - PubMed
    1. Balen A. The pathophysiology of polycystic ovary syndrome: trying to understand PCOS and its endocrinology. Best Pract Res Clin Obstet Gynaecol. 2004;18:685–706. doi: 10.1016/j.bpobgyn.2004.05.004. - DOI - PubMed
    1. Barazesh F, Mirzaei A, Abbasian Z, Ghavami Zadeh M. The Effect of Hydroalcoholic Extract of Glycyrrhizaglabra L. (licorice) Root on Serum Level of Glucose, Triglyceride and Cholesterol in Polycystic Ovary Syndrome Induced by Letrozole in Rats. Armaghane Danesh. 2016;21:148–159.

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