Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 May 15;20(5):e0323184.
doi: 10.1371/journal.pone.0323184. eCollection 2025.

Disentangling behavioral determinants of seasonal influenza vaccination in post-corona era: An integrated model approach

Affiliations

Disentangling behavioral determinants of seasonal influenza vaccination in post-corona era: An integrated model approach

So-Hyun Kim et al. PLoS One. .

Abstract

Seasonal influenza vaccination (SIV) is influenced by various factors, including sociodemographic characteristics and socioeconomic status of the recipient. Nevertheless, in the post-COVID-19 era, the importance of vaccination and group immunity has grown. Therefore, applying an integrated model to identify behavioral determinants of vaccination is needed. This study aimed to identify contextual factors affecting SIV by applying Andersen's model. We utilized secondary national datasets (n = 14,535) from the 2022 Community Health Survey conducted by the Korea Disease Control and Prevention Agency. Predisposing factors were gender and age. Enabling factors were income, educational attainment, and marital status. Need factors were presence of chronic disease, health risk behaviors (smoking and/or drinking alcohol), physical activity, and coronavirus disease 2019 (COVID-19) vaccination status. Dependent variable was influenza vaccination status. Multiple binomial logistic regression analyses were performed to identify predictors of influenza vaccination status among Korean adults, stratified by gender and age. According to the results, in men, higher education increased the likelihood of influenza vaccination by 1.089 times (95% CI: 1.000-1.185), while being married increased it by 1.619 times (95% CI: 1.413-1.856); however, smoking and binge drinking reduced the likelihood by 0.822 times (95% CI: 0.732-0.923) and 0.749 times (95% CI: 0.650-0.864), respectively. Among young men, marriage (OR=1.480, 95% CI: 1.131-1.935) and physical activity (OR=1.381, 95% CI: 1.053-1.811) were significant positive factors, while among older men, chronic disease presence increased vaccination likelihood by 1.339 times (95% CI: 1.126-1.592). In women, higher education (OR=1.168, 95% CI: 1.075-1.270) and marriage (OR=2.242, 95% CI: 1.965-2.557) were strong positive predictors, while COVID-19 vaccination history consistently increased influenza vaccination likelihood (OR=1.852, 95% CI: 1.712-2.003). Among young women, smoking reduced vaccination likelihood (OR=0.551, 95% CI: 0.359-0.847), while among older women, having a chronic disease increased vaccination likelihood by 1.354 times (95% CI: 1.133-1.619). This study empirically reveals that SIV is affected by predisposing, enabling, and need factors. To effectively intervene in individual health behaviors, it is necessary to identify characteristics of the population, provide segmented messages, and apply customized strategies.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. STROBE flow chart of this study.
Fig 2
Fig 2. Analytical framework of this study.

Similar articles

References

    1. Biggerstaff M, Cauchemez S, Reed C, Gambhir M, Finelli L. Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature. BMC Infect Dis. 2014;14:480. doi: 10.1186/1471-2334-14-480 - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention (CDC). Disease burden of influenza. 2021. Retrieved from https://www.cdc.gov/flu/about/burden/index.html
    1. Iuliano AD, Roguski KM, Chang HH, Muscatello DJ, Palekar R, Tempia S, et al.. Estimates of global seasonal influenza-associated respiratory mortality: a modelling study. Lancet. 2018;391(10127):1285–300. doi: 10.1016/S0140-6736(17)33293-2 - DOI - PMC - PubMed
    1. Osterholm MT, Kelley NS, Sommer A, Belongia EA. Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis. Lancet Infect Dis. 2012;12(1):36–44. doi: 10.1016/S1473-3099(11)70295-X - DOI - PubMed
    1. Arriola C, Garg S, Anderson EJ, Ryan PA, George A, Zansky SM, et al.. Influenza vaccination modifies disease severity among community-dwelling adults hospitalized with influenza. Clin Infect Dis. 2017;65(8):1289–97. doi: 10.1093/cid/cix468 - DOI - PMC - PubMed

Substances