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Review
. 2025 Apr 3;42(2):205-212.
doi: 10.1055/s-0045-1804492. eCollection 2025 Apr.

Common Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications

Anne Sailer  1 , Igor Latich  2 , Alexa O Levey  2
Affiliations
Review

Common Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications

Anne Sailer et al. Semin Intervent Radiol. .

Abstract

Pain is a complex interplay of psychological, immunological, and sensory experiential factors that leads to discomfort and physical suffering unique to each person. Uncontrolled pain greatly affects quality of life, a person's ability to function in society, and often results in increased healthcare costs. In order to appropriately treat a patient, knowledge of the different types of pain and various combinations of therapies is imperative. Cryoneurolysis is an important adjunctive therapy in pain management. When used in the appropriate clinical setting, it can decrease a patient's pain, opioid consumption, and improve quality of life. This article reviews common targets for cryoneurolysis based on patient pathology and discusses anatomic considerations to ensure the most efficacious and safe patient outcomes.

Keywords: cryoablation; cryoneurolysis; ganglion; interventional radiology; nerve block.

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Conflict of interest statement

Conflict of Interest I have received no money/grant from Boston Scientific. I have signed a contract as a consult, but have not received any monetary compensation as of yet, nor any type of grant money.

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