Biological physics to uncover cell signaling
- PMID: 40376425
- PMCID: PMC12075082
- DOI: 10.1007/s12551-025-01308-8
Biological physics to uncover cell signaling
Abstract
In this report, I describe some of the subjects and problems that we have addressed over the last 25 years in the area of cell signaling using the tools of biological physics. The report covers part of our work on intracellular Ca signals, pattern formation, transport of messengers in the interior of cells, quantification of biophysical parameters from experiments, and information transmission. The description includes both our modeling and experimental work highlighting how the tools of physics can give useful insights into the workings of biological systems.
Keywords: Biological physics; Cell signaling; Information.
© International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag GmbH Germany, part of Springer Nature 2025. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
Conflict of interest statement
Competing interestsThe author declares no competing interests.
Similar articles
-
The Lived Experience of Autistic Adults in Employment: A Systematic Search and Synthesis.Autism Adulthood. 2024 Dec 2;6(4):495-509. doi: 10.1089/aut.2022.0114. eCollection 2024 Dec. Autism Adulthood. 2024. PMID: 40018061 Review.
-
Measures implemented in the school setting to contain the COVID-19 pandemic.Cochrane Database Syst Rev. 2022 Jan 17;1(1):CD015029. doi: 10.1002/14651858.CD015029. Cochrane Database Syst Rev. 2022. Update in: Cochrane Database Syst Rev. 2024 May 2;5:CD015029. doi: 10.1002/14651858.CD015029.pub2. PMID: 35037252 Free PMC article. Updated.
-
A New Measure of Quantified Social Health Is Associated With Levels of Discomfort, Capability, and Mental and General Health Among Patients Seeking Musculoskeletal Specialty Care.Clin Orthop Relat Res. 2025 Apr 1;483(4):647-663. doi: 10.1097/CORR.0000000000003394. Epub 2025 Feb 5. Clin Orthop Relat Res. 2025. PMID: 39915110
-
Stigma Management Strategies of Autistic Social Media Users.Autism Adulthood. 2025 May 28;7(3):273-282. doi: 10.1089/aut.2023.0095. eCollection 2025 Jun. Autism Adulthood. 2025. PMID: 40539215
-
"We're all in it together": uniting a diverse range of professionals and people with lived experience within the development of a complex, theory-based paediatric speech and language therapy intervention.Res Involv Engagem. 2025 Jun 19;11(1):67. doi: 10.1186/s40900-025-00738-8. Res Involv Engagem. 2025. PMID: 40537841 Free PMC article.
References
-
- Abrevaya G, Ramezanian-Panahi M, Gagnon-Audet J-C, Polosecki P, Rish I, Dawson SP, Cecchi G, Dumas G (2024) Effective latent differential equation models via attention and multiple shooting. Trans Mach Learn Res. https://openreview.net/forum?id=uxNfN2PU1W
-
- Abrevaya G, Dumas G, Aravkin AY, Zheng P, Gagnon-Audet J-C, Kozloski J, Polosecki P, Lajoie G, Cox D, Dawson SP, Cecchi G, Rish I (2021) Learning brain dynamics with coupled low-dimensional nonlinear oscillators and deep recurrent networks. Neural Comput 33(8):2087–2127. 10.1162/neco_a_01401. https://direct.mit.edu/neco/article-pdf/33/8/2087/1930932/neco_a_01401.pdf - PubMed
-
- Alberts B, Bray D, Hopkin K, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2014) Essential cell biology, 4th edn. Garland Science, New York. 10.1201/9781315815015
-
- Allbritton NL, Meyer T, Stryer L (1992) Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate. Science 258(5089):1812–1815. 10.1126/science.1465619. https://www.science.org/doi/pdf/10.1126/science.1465619 - DOI - PubMed
-
- Atakpa-Adaji P, Ivanova A, Kujawa K, Taylor CW (2024) Krap regulates mitochondrial ca2+ uptake by licensing ip3 receptor activity and stabilizing er-mitochondrial junctions. J Cell Sci 137(12):261728. 10.1242/jcs.261728. https://journals.biologists.com/jcs/article-pdf/137/12/jcs261728/3559546... - PMC - PubMed
Publication types
LinkOut - more resources
Full Text Sources
