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Editorial
. 2025 Apr 30;14(4):868-871.
doi: 10.21037/tau-2025-45. Epub 2025 Apr 17.

The patients have spoken: how does enfortumab vedotin impact quality of life?

Jason R Brown  1   2
Affiliations
Editorial

The patients have spoken: how does enfortumab vedotin impact quality of life?

Jason R Brown. Transl Androl Urol. .
No abstract available

Keywords: Enfortumab vedotin (EV); advanced urothelial carcinoma (aUC); health-related quality of life; patient-reported outcomes (PROs).

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Conflict of interest statement

Conflicts of Interest: The author has completed the ICMJE uniform disclosure form (available at https://tau.amegroups.com/article/view/10.21037/tau-2025-45/coif). J.R.B. has served on advisory boards for Pfizer, EMD Serono, and Johnson & Johnson. He is also on a speakers’ bureau for Merck. The author has no other conflicts of interest to declare.

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References

    1. Powles T, Rosenberg JE, Sonpavde GP, et al. Enfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma. N Engl J Med 2021;384:1125-35. 10.1056/NEJMoa2035807 - DOI - PMC - PubMed
    1. Powles T, Valderrama BP, Gupta S, et al. Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer. N Engl J Med 2024;390:875-88. 10.1056/NEJMoa2312117 - DOI - PubMed
    1. Rosenberg JE, Powles T, Sonpavde GP, et al. EV-301 long-term outcomes: 24-month findings from the phase III trial of enfortumab vedotin versus chemotherapy in patients with previously treated advanced urothelial carcinoma. Ann Oncol 2023;34:1047-54. 10.1016/j.annonc.2023.08.016 - DOI - PubMed
    1. Rosenberg JE, Mamtani R, Sonpavde GP, et al. Health-related quality of life in patients with previously treated advanced urothelial carcinoma from EV-301: a phase 3 trial of enfortumab vedotin versus chemotherapy. Eur Urol 2024;85:574-85. 10.1016/j.eururo.2024.01.007 - DOI - PMC - PubMed
    1. Van Hemelrijck M, Sparano F, Josephs D, et al. Patient-reported outcomes in randomised clinical trials of bladder cancer: an updated systematic review. BMC Urol 2019;19:86. 10.1186/s12894-019-0518-9 - DOI - PMC - PubMed