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Case Reports
. 2025 Jun:131:111447.
doi: 10.1016/j.ijscr.2025.111447. Epub 2025 May 14.

Novel grafting technique using femoral subcutaneous tissue in the surgical management of Peyronie's disease: A case report

Pande Made Wisnu Tirtayasa  1 , I Gede Yogi Prema Ananda  2 , Marshal Harvy Wicaksono Pantjoro  3 , Gede Wirya Kusuma Duarsa  4
Affiliations
Case Reports

Novel grafting technique using femoral subcutaneous tissue in the surgical management of Peyronie's disease: A case report

Pande Made Wisnu Tirtayasa et al. Int J Surg Case Rep. 2025 Jun.

Abstract

Introduction: Peyronie's disease (PD) is characterized by fibrous plaque formation in the tunica albuginea, leading to penile curvature, painful erections, and erectile dysfunction (ED). Surgical treatment often requires grafting post-plaque excision to restore function. Although various graft materials are used, the use of femoral subcutaneous tissue for PD has not been documented yet. The objective is to explore the feasibility and potential benefits of this new graft material as an alternative for PD patients.

Case presentation: A 52-year-old male with Peyronie's disease presented with penile curvature and painful erections. Physical examination revealed a penile plaque. After plaque excision, a femoral subcutaneous graft was placed. Postoperatively, the patient experienced no complications, including graft rejection, erectile dysfunction, or penile shortening, and resumed normal sexual function.

Discussion: Femoral subcutaneous tissue was selected for its high vascularity, ease of harvesting, and low complication risk. Compared to commonly used grafts, it offers better perfusion and tissue integration, reducing the risk of PD recurrence and shortening.

Conclusion: This case highlights the successful utilization of femoral subcutaneous tissue as a graft for PD surgery, offering promising results. Further research is needed to validate its long-term efficacy compared to traditional grafts.

Keywords: Femoral subcutaneous tissue; Graft; Peyronie's disease.

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Conflict of interest statement

Declaration of competing interest The authors declare no conflicts of interest.

Figures

Fig. 1
Fig. 1
Dorsal curvature after intracavernosal injection with normal saline.
Fig. 2
Fig. 2
Plaque exposure.
Fig. 3
Fig. 3
Post dorsal plaque excision.
Fig. 4
Fig. 4
Post grafting using femoral subcutaneous tissue.
Fig. 5
Fig. 5
Illustration of the Tirtayasa-Duarsa technique (A. harvesting the subcutaneous femoral tissue from the left upper thigh below the anterior superior iliac spine; B. flipping the subcutaneous femoral tissue to expose the side with high vascularity; C. stretching the subcutaneous femoral tissue to fully cover the defect; D. grafting the subcutaneous femoral tissue into the excised penile defect; E. retracting the neurovascular bundle to avoid injury to those structures).
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