Retinopathy of prematurity in the era of precision neonatology: from risk stratification to targeted therapies

doi:10.1007/s12519-025-00919-1

Editorial

. 2025 May;21(5):430-435.

doi: 10.1007/s12519-025-00919-1.

Retinopathy of prematurity in the era of precision neonatology: from risk stratification to targeted therapies

Luca Filippi¹, Silvia Gulden², Maurizio Cammalleri³, Gabriella Araimo², Giacomo Cavallaro⁴, Eduardo Villamor⁵

Affiliations

¹ Department of Clinical and Experimental Medicine, Neonatology and Neonatal Intensive Care Unit, University of Pisa, Pisa, 56124, Italy.
² Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy.
³ Department of Biology, University of Pisa, Pisa, 56124, Italy.
⁴ Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy. giacomo.cavallaro@policlinico.mi.it.
⁵ Division of Neonatology, MosaKids Children's Hospital, Maastricht University Medical Centre (MUMC+), Research Institute for Oncology and Reproduction (GROW), Maastricht University, P. Debyelaan 25, Maastricht, 6229HX, The Netherlands. e.villamor@mumc.nl.

PMID: 40380041
DOI: 10.1007/s12519-025-00919-1

Editorial

Retinopathy of prematurity in the era of precision neonatology: from risk stratification to targeted therapies

Luca Filippi et al. World J Pediatr. 2025 May.

. 2025 May;21(5):430-435.

doi: 10.1007/s12519-025-00919-1.

Authors

Luca Filippi¹, Silvia Gulden², Maurizio Cammalleri³, Gabriella Araimo², Giacomo Cavallaro⁴, Eduardo Villamor⁵

Affiliations

¹ Department of Clinical and Experimental Medicine, Neonatology and Neonatal Intensive Care Unit, University of Pisa, Pisa, 56124, Italy.
² Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy.
³ Department of Biology, University of Pisa, Pisa, 56124, Italy.
⁴ Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy. giacomo.cavallaro@policlinico.mi.it.
⁵ Division of Neonatology, MosaKids Children's Hospital, Maastricht University Medical Centre (MUMC+), Research Institute for Oncology and Reproduction (GROW), Maastricht University, P. Debyelaan 25, Maastricht, 6229HX, The Netherlands. e.villamor@mumc.nl.

PMID: 40380041
DOI: 10.1007/s12519-025-00919-1

No abstract available

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Conflict of interest statement

Declarations. Conflict of interest: No financial or non-financial benefits have been received or will be received from any party related directly or indirectly to the subject of this article. Ethical approval: Not applicable.

References

1. Freitas AM, Mörschbächer R, Thorell MR, Rhoden EL. Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study. Int J Retina Vitreous. 2018;4:20. - PubMed - PMC - DOI
1. Holmström G, Broberger U, Thomassen P. Neonatal risk factors for retinopathy of prematurity—a population-based study. Acta Ophthalmol Scand. 1998;76:204–7. - PubMed - DOI
1. Gilbert C. Retinopathy of prematurity: a global perspective of the epidemics, population of babies at risk and implications for control. Early Hum Dev. 2008;84:77–82. - PubMed - DOI
1. Dammann O, Hartnett ME, Stahl A. Retinopathy of prematurity. Dev Med Child Neurol. 2023;65:625–31. - PubMed - DOI
1. Gilbert C, Malik ANJ, Nahar N, Das SK, Visser L, Sitati S, et al. Epidemiology of ROP update–Africa is the new frontier. Semin Perinatol. 2019;43:317–22. - PubMed - DOI

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[1] Freitas AM, Mörschbächer R, Thorell MR, Rhoden EL. Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study. Int J Retina Vitreous. 2018;4:20. - PubMed - PMC - DOI

[2] Freitas AM, Mörschbächer R, Thorell MR, Rhoden EL. Incidence and risk factors for retinopathy of prematurity: a retrospective cohort study. Int J Retina Vitreous. 2018;4:20. - PubMed - PMC - DOI

[3] Holmström G, Broberger U, Thomassen P. Neonatal risk factors for retinopathy of prematurity—a population-based study. Acta Ophthalmol Scand. 1998;76:204–7. - PubMed - DOI

[4] Holmström G, Broberger U, Thomassen P. Neonatal risk factors for retinopathy of prematurity—a population-based study. Acta Ophthalmol Scand. 1998;76:204–7. - PubMed - DOI

[5] Gilbert C. Retinopathy of prematurity: a global perspective of the epidemics, population of babies at risk and implications for control. Early Hum Dev. 2008;84:77–82. - PubMed - DOI

[6] Gilbert C. Retinopathy of prematurity: a global perspective of the epidemics, population of babies at risk and implications for control. Early Hum Dev. 2008;84:77–82. - PubMed - DOI

[7] Dammann O, Hartnett ME, Stahl A. Retinopathy of prematurity. Dev Med Child Neurol. 2023;65:625–31. - PubMed - DOI

[8] Dammann O, Hartnett ME, Stahl A. Retinopathy of prematurity. Dev Med Child Neurol. 2023;65:625–31. - PubMed - DOI

[9] Gilbert C, Malik ANJ, Nahar N, Das SK, Visser L, Sitati S, et al. Epidemiology of ROP update–Africa is the new frontier. Semin Perinatol. 2019;43:317–22. - PubMed - DOI

[10] Gilbert C, Malik ANJ, Nahar N, Das SK, Visser L, Sitati S, et al. Epidemiology of ROP update–Africa is the new frontier. Semin Perinatol. 2019;43:317–22. - PubMed - DOI

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Retinopathy of prematurity in the era of precision neonatology: from risk stratification to targeted therapies

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Retinopathy of prematurity in the era of precision neonatology: from risk stratification to targeted therapies

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Conflict of interest statement

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