Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1985 Jul 15;229(2):353-9.
doi: 10.1042/bj2290353.

Comparison of human lactoferrins from milk and neutrophilic leucocytes. Relative molecular mass, isoelectric point, iron-binding properties and uptake by the liver

N Moguilevsky, L A Retegui, P L Masson
Comparative Study

Comparison of human lactoferrins from milk and neutrophilic leucocytes. Relative molecular mass, isoelectric point, iron-binding properties and uptake by the liver

N Moguilevsky et al. Biochem J. .

Abstract

Human lactoferrins isolated from neutrophilic leucocytes and milk by CM-Sephadex chromatography were similar in Mr (76000) and pI (8.7). Upon acidification, both proteins released their two Fe3+ ions/molecule in a similar biphasic way. Both proteins intravenously injected into mice were cleared from plasma at the same rate. The maximal uptakes by the liver, which occurred 5 min after injection, were inhibited to the same extent by milk lactoferrin used as a competitor.

PubMed Disclaimer

References

    1. Int Arch Allergy Appl Immunol. 1966;29(2):185-9 - PubMed
    1. J Biol Chem. 1969 Aug 25;244(16):4406-12 - PubMed
    1. J Exp Med. 1969 Sep 1;130(3):643-58 - PubMed
    1. J Exp Med. 1970 Mar 1;131(3):559-70 - PubMed
    1. Eur J Biochem. 1971 Jun 11;20(3):420-5 - PubMed

Publication types