Luspatercept in lower-myelodysplastic syndromes (MDS): Real-world data from the Gruppo Romano-Laziale Mielodisplasie (GROM-L) and review of literature

Affiliations

¹ Hematology, Department of Clinical and Molecular Medicine, University Hospital Sant'Andrea-Sapienza, Rome, Italy.
² Hematology, AOU Policlinico Tor Vergata, Rome, Italy.
³ Hematology and Stem Cell Transplantation Unit, Campus Bio-Medico University, Rome, Italy.
⁴ Hematology Unit, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Rome, Italy.
⁵ Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.
⁶ Haematology Department, San Giovanni-Addolorata Hospital, Rome, Italy.
⁷ U.O.S. Hematology ASL Roma 1, Rome, Italy.
⁸ Hematology, Department of Translational and Precision Medicine, Az. Policlinico Umberto I-Sapienza University, Rome, Italy.
⁹ Department of Hematology, Polo Universitario Pontino, S.M. Goretti Hospital, Latina, Italy.
¹⁰ Haematology and Haematopoietic Stem Cells Transplant Unit, AO San Camillo-Forlanini, Rome, Italy.
¹¹ U.O.C. Ematologia Ospedale Belcolle Viterbo, Viterbo, Italy.

Sabrina Mariani et al. Leuk Res. 2025 Jul.

. 2025 Jul:154:107715.

doi: 10.1016/j.leukres.2025.107715. Epub 2025 May 13.

¹ Hematology, Department of Clinical and Molecular Medicine, University Hospital Sant'Andrea-Sapienza, Rome, Italy.
² Hematology, AOU Policlinico Tor Vergata, Rome, Italy.
³ Hematology and Stem Cell Transplantation Unit, Campus Bio-Medico University, Rome, Italy.
⁴ Hematology Unit, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Rome, Italy.
⁵ Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.
⁶ Haematology Department, San Giovanni-Addolorata Hospital, Rome, Italy.
⁷ U.O.S. Hematology ASL Roma 1, Rome, Italy.
⁸ Hematology, Department of Translational and Precision Medicine, Az. Policlinico Umberto I-Sapienza University, Rome, Italy.
⁹ Department of Hematology, Polo Universitario Pontino, S.M. Goretti Hospital, Latina, Italy.
¹⁰ Haematology and Haematopoietic Stem Cells Transplant Unit, AO San Camillo-Forlanini, Rome, Italy.
¹¹ U.O.C. Ematologia Ospedale Belcolle Viterbo, Viterbo, Italy.

No abstract available

Keywords: Low risk myelodysplastic syndrome; Luspatercept; Myelodisplastic syndrome; Real-life; Real-word.

Conflict of interest statement

Declaration of Competing Interest The authors declare no conflict of interest.