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Case Reports
. 2025 Apr 17;17(4):e82431.
doi: 10.7759/cureus.82431. eCollection 2025 Apr.

A Case of Low T1 Mapping Values in Myocardial Calcifications in a Patient With End-Stage Renal Disease

Ahmed Abdelmonem  1 , Ahmed S Negm  1 , Subhi Al'Aref  2 , Kedar Jambhekar  1
Affiliations
Case Reports

A Case of Low T1 Mapping Values in Myocardial Calcifications in a Patient With End-Stage Renal Disease

Ahmed Abdelmonem et al. Cureus. .

Abstract

Cardiac MRI is the gold standard in diagnosing many cardiac pathologies. T1 mapping, a novel cardiac MRI sequence, provides precise assessment and characterization of myocardial tissue. Low T1 values have been reported in specific entities, including Fabry disease and iron overload. We report a case of decreased T1 values with diffuse myocardial calcifications in a 24-year-old female with end-stage renal disease. This case provides valuable new insights into T1 mapping, particularly regarding the association between myocardial calcifications and low T1 values, a connection that has only been reported in a single prior study.

Keywords: cardiac mri; diffuse myocardial calcifications; end-stage renal disease (esrd); t1 mapping; tissue characterization.

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Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. Non-contrast axial CT of the chest showing significant cardiomegaly with diffuse hyperdense calcifications in the left ventricular myocardium. Bilateral pleural effusions (more profound on the right) are also seen.
Figure 2
Figure 2. Cardiac CT with short-axis views showing diffuse hyperdense calcifications in the left ventricular myocardium. Pleural effusion is also seen.
Figure 3
Figure 3. CT of the abdomen and pelvis demonstrating atrophic kidneys, consistent with the patient’s diagnosis of end-stage renal disease.
Figure 4
Figure 4. Cardiac MRI with short-axis imaging demonstrating hypertrophy of the left ventricular wall.
Figure 5
Figure 5. T1 parametric map demonstrating diffuse low T1 values corresponding to the diffuse hyperdensity seen on the CT.
See this image and copyright information in PMC

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