Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Apr 2:30:101795.
doi: 10.1016/j.ssmph.2025.101795. eCollection 2025 Jun.

The contribution of social determinants of health to long-term outcomes following traumatic brain injury

John D Corrigan  1 , Mike Vuolo  1 , Rebecca Shankman  1 , Jennifer Bogner  1 , Cynthia L Beaulieu  1 , Amanda L Botticello  2 , Kathryn A Hyzak  1 , Shannon Juengst  3 , Raj G Kumar  4 , Cecilia Mengo  1
Affiliations

The contribution of social determinants of health to long-term outcomes following traumatic brain injury

John D Corrigan et al. SSM Popul Health. .

Abstract

Social Determinants of Health (SDoH) are a significant factor in health outcomes for both acute and chronic health conditions, but systematic research related to outcomes from traumatic brain injury (TBI) has been limited. This study explores the relationship between individual and neighborhood-level SDoH and TBI outcomes to understand the extent of their influence on long-term recovery. Hybrid panel models that decompose time-varying predictors into between- and within-person effects were used to examine the relationships between SDoH and participation in the community, life satisfaction, and global functioning for persons with moderate to severe TBI one to 30 years post-injury. Participants were 9263 persons, distributed nationally, who received inpatient rehabilitation for TBI and enrolled in the TBI Model Systems longitudinal study. Individual-level SDoH included sex, race/ethnicity, education, employment, insurance, primary means of transportation, and rurality. The Social Vulnerability Index (SVI) was used as an indicator of neighborhood disadvantage. Results indicated that neighborhood-level SDoH accounted for differences in outcomes between individuals but not due to change in a given individual's neighborhood. These findings were robust to the inclusion of numerous individual-level SDoH, which were also associated with the outcomes. Individual-level SDoH accounted for differences in outcomes both between individuals and with change in a given individual's status. Among four thematic subscales constituting the SVI, the socio-economic status subscale was consistently associated with all three outcomes.

Keywords: Neighborhood disadvantage; Social determinants of health; Traumatic brain injury.

PubMed Disclaimer

Conflict of interest statement

None of the authors have financial or personal relationships with other people or organizations that could inappropriately influence or bias this work and thus have nothing to declare.

Figures

Fig. 1
Fig. 1
Center for disease control and prevention social vulnerability index Subthemes (Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry/Geospatial ResearchAnalysisand Services Program, 2022).
Fig. 2
Fig. 2
Coefficient Plot of Individual Level Social Determinants of Health (PART = Participation Assessment with Recombined Tools, SWLS = Satisfaction With Life Scale, GOS-E = Glasgow Outcome Scale–Extended, HS = high school).
Fig. 3
Fig. 3
Coefficient plot of overall and subtheme SVI scores (part = participation assessment with recombined tools, SWLS = satisfaction with life scale, GOS-e = glasgow outcome scale–extended).
See this image and copyright information in PMC

References

    1. Anusic I., Yap S.C.Y., Lucas R.E. Testing set-point theory in a Swiss national sample: Reaction and adaptation to major life events. Social Indicators Research. 2014;119(3):1265–1288. doi: 10.1007/s11205-013-0541-2. - DOI - PMC - PubMed
    1. Arango-Lasprilla J.C., Ketchum J.M., Gary K., Hart T., Corrigan J., Forster L., et al. Race/ethnicity differences in satisfaction with life among persons with traumatic brain injury. NeuroRehabilitation. 2009;24(1):5–14. doi: 10.3233/NRE-2009-0449. - DOI - PubMed
    1. Arango-Lasprilla J.C., Ketchum J.M., Lewis A.N., Krch D., Gary K.W., Dodd B.A. Racial and ethnic disparities in employment outcomes for persons with traumatic brain injury: A longitudinal investigation 1-5 years after injury. PM & R: The Journal of Injury, Function, and Rehabilitation. 2011;3(12):1083–1091. doi: 10.1016/j.pmrj.2011.05.023. - DOI - PubMed
    1. Arango-Lasprilla J.C., Ketchum J.M., Williams K., Kreutzer J.S., Marquez de la Plata C.D., O'Neil-Pirozzi T.M., et al. Racial differences in employment outcomes after traumatic brain injury. Archives of Physical Medicine and Rehabilitation. 2008;89(5):988–995. doi: 10.1016/j.apmr.2008.02.012. - DOI - PubMed
    1. Arango-Lasprilla J.C., Rosenthal M., Deluca J., Cifu D.X., Hanks R., Komaroff E. Functional outcomes from inpatient rehabilitation after traumatic brain injury: How do Hispanics fare? Archives of Physical Medicine and Rehabilitation. 2007;88(1):11–18. doi: 10.1016/j.apmr.2006.10.029. - DOI - PubMed

LinkOut - more resources