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. 2025 Jul;16(7):1327-1339.
doi: 10.1007/s13300-025-01747-2. Epub 2025 May 20.

Expert Opinion on Optimizing Suboptimal Basal Insulin Titration in India: Addressing Challenges and Leveraging Digital Solutions

Sanjay Kalra  1 , Pramila Kalra  2 , Kalyan Kumar Gangopadhyay  3 , Sandeep Julka  4 , Om J Lakhani  5 , Manoj Chawla  6 , Santhosh Ramakrishnan  7 , Jasjeet Singh Wasir  8
Affiliations

Expert Opinion on Optimizing Suboptimal Basal Insulin Titration in India: Addressing Challenges and Leveraging Digital Solutions

Sanjay Kalra et al. Diabetes Ther. 2025 Jul.

Abstract

Basal insulin titration is crucial for achieving optimal glycemic control in patients with type 2 diabetes mellitus (T2DM), yet many patients and healthcare providers encounter persistent challenges in adjusting insulin doses to meet individualized targets. In October 2024, an expert panel of digital health specialists comprising endocrinologists, and diabetologists convened to discuss the limitations associated with suboptimal basal insulin titration and explore the potential of digital health solutions to address these issues. The discussion focused on how digital health tools like app-based services could facilitate more effective self-management, enhance patient engagement, and enable real-time communication in T2DM management. The panel's deliberations underscored the promise of digital health technologies as one of the means to overcome current complexities in basal insulin titration. By leveraging real-time data monitoring, remote consultations, and tailored treatment approaches, these tools offer a scalable progress to improving glycemic outcomes and overall diabetes management.

Keywords: Digital health; India; Suboptimal insulin titration; Type 2 diabetes mellitus.

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Conflict of interest statement

Declarations. Conflict of Interest: Authors Dr. Sanjay Kalra, Dr. Pramila Kalra, Dr. Kalyan Kumar Gangopadhyay, Dr. Sandeep Julka, Dr. Om J Lakhani, Dr. Manoj Chawla, Dr. Santhosh Ramakrishnan, and Dr. Jasjeet Singh Wasir declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Dr. Sanjay Kalra is an Editorial Board member of Diabetes Therapy. Dr. Sanjay Kalra was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. Ethical Approval: This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.

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References

    1. Ye J, Wu Y, Yang S, Zhu D, Chen F, Chen J, et al. The global, regional and national burden of type 2 diabetes mellitus in the past, present and future: a systematic analysis of the Global Burden of Disease Study 2019. Front Endocrinol. 2023;14. - PMC - PubMed
    1. Anjana RM, Unnikrishnan R, Deepa M, Pradeepa R, Tandon N, Das AK, et al. Metabolic non-communicable disease health report of India: the ICMR-INDIAB national cross-sectional study (ICMR-INDIAB-17). Lancet Diabetes Endocrinol. 2023;11(7):474–89. - PubMed
    1. Sinha R, Priya A, Sinha A, Rahman MHU. Prevalence of diabetes distress among type 2 diabetes mellitus patients in India: a systematic review and meta-analysis. Health Psychol Behav Med. 2024;12(1):2324091. - PMC - PubMed
    1. Sharma M, Gaidhane A, Choudhari SG. A comprehensive review on trends and patterns of non-communicable disease risk factors in India. Cureus. 2024;16(3): e57027. - PMC - PubMed
    1. Erukulapati RS, MMR, Jakkidi LR, Sathyanarayana SO, Ayyagari U, Ashwathiah S, et al. A practical approach to the initiation, titration and intensification of insulin therapy in adults with diabetes in the Indian Context: recommendations by Association of Clinical Endocrinologists Consensus Group. Clin Diabetol. 2024;1(1):6–42.

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