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Editorial
. 2025 Jul;12(4):e200425.
doi: 10.1212/NXI.0000000000200425. Epub 2025 May 20.

Beyond the Lab Slip: Why Laboratory Expertise Matters in Neuronal Antibody Testing and Why Clinicians Should Care

Frank Leypoldt  1
Affiliations
Editorial

Beyond the Lab Slip: Why Laboratory Expertise Matters in Neuronal Antibody Testing and Why Clinicians Should Care

Frank Leypoldt. Neurol Neuroimmunol Neuroinflamm. 2025 Jul.
No abstract available

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Conflict of interest statement

F. Leypoldt is supported by E-Rare Joint Transnational research support (ERA-Net, LE3064/2-1) ERA-NET NEURON_BB-148 MICE-AE, Stiftung Pathobiochemie of the German Society for Laboratory Medicine and HORIZON MSCA 2022 Doctoral Network 101119457 - IgG4-TREAT and discloses speaker honoraria from Grifols, Teva, Biogen, Bayer, Roche, Novartis, Fresenius, travel funding from Merck, Grifols and Bayer and serving on advisory boards for Roche, Biogen and Alexion. He works in an academic institution offering commercial antibody testing. Go to Neurology.org/NN for full disclosures.

Comment in

  • Neurol Neuroimmunol Neuroinflamm. 104:e200410.
  • Neurol Neuroimmunol Neuroinflamm. 104:e200406.

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References

    1. Graus F, Titulaer MJ, Balu R, et al. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol.2016;15(4):391-404. doi: 10.1016/S1474-4422(15)00401-9 - DOI - PMC - PubMed
    1. Graus F, Vogrig A, Muñiz-Castrillo S, et al. Updated diagnostic criteria for paraneoplastic neurologic syndromes. Neurol Neuroimmunol Neuroinflamm. 2021;8(4):e1014. doi: 10.1212/nxi.0000000000001014 - DOI - PMC - PubMed
    1. Milano C, Businaro P, Papi C, et al. Assessing commercial tissue-based assays for autoimmune neurological disorders (I): antibodies to intracellular antigens. Neurol Neuroimmunol Neuroinflamm. 2025;12(4):e200410. doi: 10.1212/NXI.0000000000200410. - DOI - PMC - PubMed
    1. Papi C, Milano C, Arlettaz L, et al. Assessing commercial tissue-based assays for autoimmune neurological disorders (II): antibodies to surface antigens. Neurol Neuroimmunol Neuroinflamm. 2025;12(4):e200406. doi: 10.1212/NXI.0000000000200406. - DOI - PMC - PubMed
    1. Déchelotte B, Muñiz-Castrillo S, Joubert B, et al. Diagnostic yield of commercial immunodots to diagnose paraneoplastic neurologic syndromes. Neurol Neuroimmunol Neuroinflamm. 2020;7(3):e701. doi: 10.1212/nxi.0000000000000701 - DOI - PMC - PubMed

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